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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2023-8.3.7</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-4209</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Особенности клинической симптоматики и данных ЭКГ у женщин с острым коронарным синдромом</article-title><trans-title-group xml:lang="en"><trans-title>Clinical symptoms and ECG data in women with acute coronary syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0963-4793</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сумин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sumin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сумин Алексей Николаевич – доктор медицинских наук, заведующий лабораторией коморбидности при сердечно-сосудистых заболеваниях отдела клинической кардиологии</p><p>650002, г. Кемерово, Сосновый б-р, 6, Россия </p></bio><bio xml:lang="en"><p>Aleksey N. Sumin – Dr. Sc. (Med.), Head of the Laboratory of Comorbidity in Cardiovascular Diseases, Department of Clinical Cardiology</p><p>Sosnovy blvd 6, Kemerovo 650002, Russian Federation </p></bio><email xlink:type="simple">an_sumin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вахрушев</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Vakhrushev</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вахрушев Александр Константинович – кандидат медицинских наук доцент кафедры кардиологии</p><p>125993, г. Москва, ул. Баррикадная, 2/1, стр. 1, Россия </p></bio><bio xml:lang="en"><p>Alexander K. Vakhrushev – Cand. Sc. (Med.), Associate Professor at Department of Cardiology</p><p>Barrikadnaya str. 2/1 build. 1, Moscow 125993, Russian Federation </p></bio><email xlink:type="simple">ak191919@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4108-164X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щеглова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcheglova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щеглова Анна Викторовна – кандидат медицинских наук, научный сотрудник лаборатории коморбидности при сердечно-сосудистых заболеваниях отдела клинической кардиологии</p><p>650002, г. Кемерово, Сосновый б-р, 6, Россия</p></bio><bio xml:lang="en"><p>Anna V. Shcheglova – Cand. Sc. (Med.), Research Officer at the Laboratory of Comorbidity in Cardiovascular Diseases, Department of Clinical Cardiology</p><p>Sosnovy blvd 6, Kemerovo 650002, Russian Federation </p></bio><email xlink:type="simple">nura.karpovitch@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»</institution></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Новокузнецкий государственный институт усовершенствования врачей – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution></aff><aff xml:lang="en"><institution>Novokuznetsk State Institute for Institute for Advanced Medical Education – Branch Campus of the Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>11</day><month>07</month><year>2023</year></pub-date><volume>8</volume><issue>3</issue><fpage>70</fpage><lpage>80</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сумин А.Н., Вахрушев А.К., Щеглова А.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сумин А.Н., Вахрушев А.К., Щеглова А.В.</copyright-holder><copyright-holder xml:lang="en">Sumin A.N., Vakhrushev A.K., Shcheglova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/4209">https://www.actabiomedica.ru/jour/article/view/4209</self-uri><abstract><p>Существует много различий в симптомах боли в груди между мужчинами и женщинами в отношении локализации, характера и дополнительных симптомов. Остаётся актуальным вопрос описания различий болевого синдрома в груди у мужчин и женщин с острым коронарным синдром (ОКС), а также соотнесение их с изменениями электрокардиограммы (ЭКГ) и данными коронароангигорафии (КАГ).</p><sec><title>Методы</title><p>Методы. В исследование были включены 588 пациентов кардиологического отделения ГБУЗО КО «Новокузнецкая городская клиническая больница № 1» с 2013 по 2017 г. с диагнозом ОКС. В зависимости от половой принадлежности исследуемых разделили на две группы: I группа – 330 мужчин; II группа – 258 женщин.</p></sec><sec><title>Результаты</title><p>Результаты. ОКС с подъёмом сегмента ST (ОКС пST) чаще наблюдался у мужчин (45,8 %), чем у женщин (33,3 %; p = 0,002). Патологических изменений на ЭКГ у женщин не было в 58,1 % случаев, у мужчин – в 45,5 % (р &lt; 0,001). Тип ЭКГ Q/пST чаще выявлялся у мужчин (45,8 %), чем у женщин (33,3 %; p = 0,002). Отсутствие поражения коронарных артерий (КА) отмечено у 27,9 % мужчин и у 44,2 % женщин (р &lt; 0,001). Гемодинамически значимый стеноз КА чаще встречался у мужчин (57,6 %), чем у женщин (38,7 %; р &lt; 0,001). При типичной клинике стенокардии гемодинамически значимое поражение КА у больных ОКС Q/бпST (без подъёма сегмента ST) выявлено в 40,2 % случаев у мужчин и в 58,5 % – у женщин (р = 0,002). При атипичной клинике стенокардии гемодинамически значимые поражения КА встречались чаще у мужчин (40,6 %), чем у женщин (34,1 %; р = 0,02).</p></sec><sec><title>Заключение</title><p>Заключение. У женщин чаще, чем у мужчин, выявляли атипичные боли в грудной клетке, интактные КА и реже – гемодинамически значимые стенозы КА. У мужчин выявлена более выраженная патология коронарных артерий при ОКС, у женщин – большие трудности диагностики ОКС.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. There are many differences in chest pain symptoms between men and women in terms of location, nature, and additional symptoms. The issue of describing the differences in chest pain in men and women with acute coronary syndrome (ACS), as well as their correlation with changes in the electrocardiogram (ECG) and coronary angiography (CAG) remains relevant.</p></sec><sec><title>Methods</title><p>Methods. The study included 588 patients of the cardiology department of the Novokuznetsk City Clinical Hospital No. 1 from 2013 to 2017 with a diagnosis of ACS. Depending on the gender, the subjects were divided into two groups: Group I – 330 men; Group II – 258 women.</p></sec><sec><title>Results</title><p>Results. ACS with ST elevation was more common in men (45.8 %) than in women (33.3 %; p = 0.002). There were no pathological ECG changes in women in 58.1 % of cases, in men – in 45.5 % (p &lt; 0.001). ECG type Q/ST elevation was detected more often in men (45.8 %) than in women (33.3 %; p = 0.002). The absence of coronary artery lesions was observed in 27.9 % of men and 44.2 % of women (p &lt; 0.001). Hemodynamically significant coronary artery stenosis was more common in men (57.6 %) than in women (38.7 %; p &lt; 0.001). In a typical angina clinic, hemodynamically significant coronary artery disease in patients with Q/without ST elevation ACS was detected in 40.2 % of men and in 58.5 % of women (p = 0.002). In the atypical angina clinic, hemodynamically significant lesions of coronary artery were more common in men (40.6 %) than in women (34.1 %; p = 0.02).</p></sec><sec><title>Conclusion</title><p>Conclusion. In women atypical chest pains and intact coronary arteries were detected more often than in men, and hemodynamically significant coronary artery stenosis were found less often than in men. In men, a more pronounced pathology of the coronary arteries in ACS was revealed, in women – great difficulties in diagnosing ACS.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>острый коронарный синдром</kwd><kwd>гендерные различия</kwd><kwd>диагностика коронарных симптомов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute coronary syndrome</kwd><kwd>gender differences</kwd><kwd>diagnosis of coronary symptoms</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено в рамках Комплексной научно-технической программы полного инновационного цикла «Разработка и внедрение комплекса технологий в области разведки и добычи твёрдых полезных ископаемых, обеспечения промышленной безопасности, биоремедиации, создания новых продуктов глубокой переработки из угольного сырья при последовательном снижении экологической нагрузки на окружающую среду и рисков для жизни населения» (утв. 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