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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2023-8.2.14</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-4082</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ И НЕЙРОХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY AND NEUROSURGERY</subject></subj-group></article-categories><title-group><article-title>Результаты хирургического лечения шванном крестца с распространением в полость малого таза</article-title><trans-title-group xml:lang="en"><trans-title>The results of surgical treatment of sacral schwannomas with extension into pelvic cavity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4263-9980</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пендюрин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pendyurin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пендюрин Иван Викторович – кандидат медицинских наук, заведующий нейрохирургическим отделением № 1, врач-нейрохирург, онколог.</p><p>630091, Новосибирск, ул. Фрунзе, 17</p></bio><bio xml:lang="en"><p>Ivan V. Pendyurin – Cand. Sc. (Med.), Head of the Neurosurgical Department No. 1, Neurosurgeon, Oncologist.</p><p>Frunze str. 17, Novosibirsk 630091</p></bio><email xlink:type="simple">ivan75nsk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyev</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильев Игорь Анатольевич – кандидат медицинских наук, научный сотрудник отделения нейрохирургии, врач-нейрохирург нейрохирургического отделения № 1.</p><p>630091, Новосибирск, ул. Фрунзе, 17</p></bio><bio xml:lang="en"><p>Igor A. Vasilyev – Cand. Sc. (Med.), Research Officer at the Research Department of Neurosurgery, Neurosurgeon at the Neurosurgical Department No. 1.</p><p>Frunze str. 17, Novosibirsk 630091</p></bio><email xlink:type="simple">vasilevigor500@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1658-2637</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Копылов</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kopylov</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Копылов Иван Сергеевич – врач-нейрохирург нейрохирургического отделения № 1.</p><p>630091, Новосибирск, ул. Фрунзе, 17</p></bio><bio xml:lang="en"><p>Ivan S. Kopylov – Neurosurgeon at the Neurosurgical Department No. 1.</p><p>Frunze str. 17, Novosibirsk 630091</p></bio><email xlink:type="simple">iskopylov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Новосибирский научно-исследовательский институт травматологии и ортопедии им. Я.Л. Цивьяна» Минздрава России</institution></aff><aff xml:lang="en"><institution>Novosibirsk Research Institute of Traumatology and Orthopedics named after Ya.L. Tsivyan</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>04</day><month>05</month><year>2023</year></pub-date><volume>8</volume><issue>2</issue><fpage>150</fpage><lpage>162</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пендюрин И.В., Васильев И.А., Копылов И.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Пендюрин И.В., Васильев И.А., Копылов И.С.</copyright-holder><copyright-holder xml:lang="en">Pendyurin I.V., Vasilyev I.A., Kopylov I.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/4082">https://www.actabiomedica.ru/jour/article/view/4082</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Анализ результатов хирургического лечения шванном крестца с распространением в малый таз.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведён анализ клинических результатов хирургического лечения 25 пациентов с шванномами крестцовой локализации, в том числе с вентральным распространением и ростом в полость малого таза, оперированных в клинике нейрохирургии Новосибирского НИИТО им. Я.Л. Цивьяна Минздрава России за 10 лет. Проведён анализ литературных данных, описывающих распространённость, классификации, диагностику и хирургическое лечение опухолей крестца и шванном в частности. Описаны особенности течения, диагностики и хирургического лечения опухолей данной локализации, принятые хирургические подходы.</p></sec><sec><title>Результаты</title><p>Результаты. Период наблюдения за пациентами в нашем исследовании составил в среднем 61,6 ± 2 мес. По сравнению с исходными показателями больных в послеоперационном периоде (на сроке 1 год) хороший клинический результат с регрессом симптоматики отмечен у 17 (68 %) из 25 пациентов, причём у 10 (40 %) из них имелся значительный регресс неврологических нарушений. У 3 (12 %) оперированных отмечено усугубление неврологических нарушений в виде усугубления чувствительных нарушений, у одного пациента отмечено усугубление нарушений функции тазовых органов. Радикальное удаление новообразования достигнуто в 24 (96 %) из 25 случаев; субтотальная резекция проведена у 1 (4 %) пациента. Число рецидивов и продолженного роста новообразований составило в нашей серии 12 % (3 из 25 пациентов). Летальность составила 0 %. Осложнения, встречаемые в нашей группе, были отмечены в 3 (12 %) случаях и проявлялись в виде раневой ликвореи в случаях задних доступов.</p></sec><sec><title>Заключение</title><p>Заключение. Степень радикальности резекции опухоли и клинических исходов напрямую связана с выбранным операционным доступом.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>The aim</title><p>The aim. To analyze the results of surgical treatment of sacral schwannomas with their extension into lower pelvis.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We analyzed the clinical results of surgical treatment of 25 patients with sacral schwannomas, including those with ventral extension and growth into pelvic cavity. All patients were operated at the Clinic of Neurosurgery of the Novosibirsk Research Institute of Traumatology and Orthopedics named after Ya.L. Tsivyan for a 10-year period. The analysis of literature describing prevalence, classification, diagnosis and surgical treatment of sacral tumors and schwannomas in particular was carried out. The features of the course, diagnosis and surgical treatment of sacral schwannomas and accepted surgical methods for their treatment are described.</p></sec><sec><title>Results</title><p>Results. The average follow-up period of the patients in our study was 61.6 ± 2 months. Compared with the initial indicators of patients in the postoperative period (1 year after the surgery), a good clinical result with the regression of symptoms was registered in 17 (68 %) out of 25 patients, and 10 (40 %) of them had a significant regression of neurological disorders. 3 (12 %) operated patients had a deterioration of neurological disorders in the form of aggravation of sensitive disorders; one patient had an aggravation of pelvic organ dysfunction. Radical removal of the tumor was achieved in 24 (96 %) out of 25 cases; subtotal resection was performed in 1 (4 %) patient. The number of relapses and continued growth of tumors in our series was 12 % (3 out of 25 patients). The mortality rate was 0 %. The complications were registered in 3 (12 %) cases and manifested as wound liquorrhea in cases of using posterior approach.</p></sec><sec><title>Conclusion</title><p>Conclusion. The degree of radicality of tumor resection and clinical outcomes is directly related to the selected surgical approach.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>шванномы крестца</kwd><kwd>невринома забрюшинного пространства</kwd><kwd>опухоли забрюшинного пространства малого таза и передней стенки крестца</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sacral schwannomas</kwd><kwd>retroperitoneal space neurinoma</kwd><kwd>tumors of the retroperitoneal space of the pelvis and the anterior wall of the sacrum</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Степанова Ю.А., Гришанков С.А., Карельская Н.А., Калинин Д.В., Глотов А.В. 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