<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2023-8.1.12</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-3993</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ И НЕЙРОХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY AND NEUROSURGERY</subject></subj-group></article-categories><title-group><article-title>Роль спинального жирового индекса в прогнозировании риска развития септического спондилодисцита после выполнения чрескожной лазерной декомпрессии поясничных межпозвонковых дисков</article-title><trans-title-group xml:lang="en"><trans-title>The role of spine adipose index in predicting the risk for septic spondylodiscitis after lumbar percutaneous laser disc decompression</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9039-9147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Степанов Иван Андреевич – ассистент кафедры общей хирургии, </p><p>664003, г. Иркутск, ул. Красного Восстания, 1</p></bio><bio xml:lang="en"><p>Ivan A. Stepanov – Teaching Assistant at the Department of General Surgery, </p><p>Krasnogo Vosstaniya str. 1, Irkutsk 664003</p></bio><email xlink:type="simple">stepanovivanneuro@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3299-1924</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белобородов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Beloborodov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белобородов Владимир Анатольевич – доктор медицинских наук, профессор, заведующий кафедрой общей хирургии, </p><p>664025, г. Иркутск, ул. Горького, 8</p></bio><bio xml:lang="en"><p>Vladimir A. Beloborodov – Dr. Sc. (Med.), Professor, Head of the Department of General Surgery, </p><p>Gorkogo str. 8, Irkutsk 664025</p></bio><email xlink:type="simple">BVA555@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Харлампиевская клиника»</institution></aff><aff xml:lang="en"><institution>Kharlampievskaya Clinic</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>09</day><month>03</month><year>2023</year></pub-date><volume>8</volume><issue>1</issue><fpage>108</fpage><lpage>116</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Степанов И.А., Белобородов В.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Степанов И.А., Белобородов В.А.</copyright-holder><copyright-holder xml:lang="en">Stepanov I.A., Beloborodov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/3993">https://www.actabiomedica.ru/jour/article/view/3993</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Изучить роль спинального жирового индекса (СЖИ) в прогнозировании риска развития септического спондилодисцита после выполнения чрескожной лазерной декомпрессии (ЧЛДД) поясничных межпозвонковых дисков.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Выполнено ретроспективное наблюдательное одноцентровое исследование. Изучены различные клинико-инструментальные параметры, в том числе спинальный жировой индекс, потенциально являющиеся факторами риска развития постпроцедурного септического спондилодисцита.</p></sec><sec><title>Результаты</title><p>Результаты. В исследование включено 219 пациентов, которым выполнена процедура ЧЛДД по поводу дегенеративного заболевания поясничных межпозвонковых дисков. Средний период послеоперационного наблюдения за респондентами составил 30,8  ±  13,3  месяца. Признаки септического спондилодисцита выявлены в 5 (2,28 %) случаях. Многофакторный анализ показал, что III  степень операционно-анестезиологического риска по  шкале Американского общества анестезиологов (ASA, American Society of Anaesthesiologists) (р = 0,021), высокое значение индекса массы тела (более 25 кг/м2) (р = 0,043), а также большое значение СЖИ (свыше 0,7) (р = 0,037) статистически значимо связаны с развитием септического спондилодисцита у пациентов, перенёсших процедуру ЧЛДД на поясничном уровне.</p></sec><sec><title>Заключение</title><p>Заключение. Значение СЖИ статистически значимо связано с развитием спондилодисцита у пациентов, перенёсших процедуру ЧЛДД по поводу дегенеративного заболевания поясничных межпозвонковых дисков. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>The aim</title><p>The aim. To analyze the role of the spine adipose index (SAI) in predicting the risk of septic spondylodiscitis after lumbar percutaneous laser disk decompression (PLDD).</p></sec><sec><title>Material and methods</title><p>Material and methods. A retrospective observational single-center study was performed. Various clinical and instrumental parameters have been studied, including the spine adipose index, which are potential risk factors for the development of postprocedural septic spondylodiscitis.</p></sec><sec><title>Results</title><p>Results. The study included 219  patients who underwent PLDD for degenerative lumbar disk disease. The average period of postoperative observation was  30.8  ±  13.3  months. Signs of septic spondylodiscitis were detected in 5 (2.28%) cases. Multivariate analysis showed that III degree of anesthesiological risk by the American Society of Anesthesiologists (ASA) scale (p = 0.021), a high value of body mass index (more than 25 kg/m2) (p = 0.043) and a high value of SAI (over 0.7) (p = 0.037) are statistically significantly associated with the development of septic spondylodiscitis in patients who underwent lumbar PLDD.</p></sec><sec><title>Conclusion</title><p>Conclusion. The value of SAI is statistically significantly associated with the development of spondylodiscitis in patients who underwent PLDD for degenerative lumbar disk disease. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>септический спондилодисцит</kwd><kwd>спинальный жировой индекс</kwd><kwd>факторы риска</kwd><kwd>чрескожная лазерная декомпрессия межпозвонковых дисков</kwd></kwd-group><kwd-group xml:lang="en"><kwd>septic spondylodiscitis</kwd><kwd>spine adipose index</kwd><kwd>risk factors</kwd><kwd>percutaneous laser disk decompression</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Márquez Sánchez P. Spondylodiscitis. Radiologia. 2016; 58(1): 50-59. doi: 10.1016/j.rx.2015.12.005</mixed-citation><mixed-citation xml:lang="en">Márquez Sánchez  P. Spondylodiscitis. Radiologia. 2016; 58(1): 50-59. doi: 10.1016/j.rx.2015.12.005</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gouliouris T, Aliyu SH, Brown NM. Spondylodiscitis: Update on diagnosis and management. J Antimicrob Chemother. 2010; 65(3): 11-24. doi: 10.1093/jac/dkq303</mixed-citation><mixed-citation xml:lang="en">Gouliouris T, Aliyu SH, Brown NM. Spondylodiscitis: Update on diagnosis and management. J  Antimicrob Chemother. 2010; 65(3): 11-24. doi: 10.1093/jac/dkq303</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Gerometta A, Bittan F, Rodriguez Olaverri JC. Postoperative spondilodiscitis. Int Orthop. 2012; 36(2): 433-438. doi: 10.1007/s00264-011-1442-0</mixed-citation><mixed-citation xml:lang="en">Gerometta A, Bittan F, Rodriguez Olaverri JC. Postoperative spondilodiscitis. Int Orthop. 2012; 36(2): 433-438. doi: 10.1007/s00264-011-1442-0</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Herren C, Jung N, Pishnamaz M, Breuninger M, Siewe J, Sobottke R. Spondylodiscitis: Diagnosis and treatment options. Dtsch Arztebl Int. 2017; 114(51-52): 875-882. doi: 10.3238/arztebl.2017.0875</mixed-citation><mixed-citation xml:lang="en">Herren  C, Jung  N, Pishnamaz  M, Breuninger  M, Siewe  J, Sobottke  R. Spondylodiscitis: Diagnosis and treatment options. Dtsch Arztebl Int. 2017; 114(51-52): 875-882. doi:  10.3238/arztebl.2017.0875</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Винокуров A.C., Беленькая O.И., Юдин A.Л., Ким A.В. Современная диагностика спондилодисцитов: основные КТ- и МР-признаки. Лучевая диагностика и терапия. 2019; (1): 39-47.</mixed-citation><mixed-citation xml:lang="en">Vinokurov AS, Belenkaya OI, Yudin AL, Kim AV. Spondylodiscitis diagnostics in nowadays: Basic CT and MRI signs. Diagnostic Radiology and Radiotherapy. 2019; (1): 39-47. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gentile L, Benazzo F, De Rosa F, Boriani S, Dallagiacoma G, Franceschetti G, et al. A systematic review: Characteristics, complications and treatment of spondylodiscitis. Eur Rev Med Pharmacol Sci. 2019; 23(Suppl 2): 117-128. doi: 10.26355/eurrev_201904_17481</mixed-citation><mixed-citation xml:lang="en">Gentile L, Benazzo F, De Rosa F, Boriani S, Dallagiacoma G, Franceschetti G, et al. A systematic review: Characteristics, complications and treatment of spondylodiscitis. Eur Rev Med Pharmacol Sci. 2019; 23(Suppl 2): 117-128. doi: 10.26355/eurrev_201904_17481</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Zarghooni K, Röllinghoff M, Sobottke R, Eysel P. Treatment of spondylodiscitis. Int Orthop. 2012; 36(2): 405-411. doi: 10.1007/s00264-011-1425-1</mixed-citation><mixed-citation xml:lang="en">Zarghooni K, Röllinghoff M, Sobottke R, Eysel P. Treatment of spondylodiscitis. Int Orthop. 2012; 36(2): 405-411. doi: 10.1007/s00264-011-1425-1</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta VK, Zhou Y, Manson JF, Watt JP. Radiographic spine adipose index: An independent risk factor for deep surgical site infection after posterior instrumented lumbar fusion. Spine J. 2021; 21(10): 1711-1717. doi: 10.1016/j.spinee.2021.04.005</mixed-citation><mixed-citation xml:lang="en">Gupta VK, Zhou Y, Manson JF, Watt JP. Radiographic spine adipose index: An independent risk factor for deep surgical site infection after posterior instrumented lumbar fusion. Spine J. 2021; 21(10): 1711-1717. doi: 10.1016/j.spinee.2021.04.005</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies. Int J Surg. 2014; 12(12): 1495-1499. doi: 10.1016/j.ijsu.2014.07.013</mixed-citation><mixed-citation xml:lang="en">von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies. Int  J Surg. 2014; 12(12): 1495-1499. doi: 10.1016/j.ijsu.2014.07.013</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ассоциация нейрохирургов России. Клинические рекомендации по диагностике и лечению воспалительных заболеваний позвоночника и спинного мозга. М.; 2015.</mixed-citation><mixed-citation xml:lang="en">Association of Neurosurgeons of Russia. Clinical guidelines for the diagnosis and treatment of inflammatory diseases of the spine and spinal cord. Moscow; 2015. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">World Medical Association. World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAMA. 2013; 310(20): 2191-2194. doi: 10.1001/jama.2013.281053</mixed-citation><mixed-citation xml:lang="en">World Medical Association. World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAMA. 2013; 310(20): 2191-2194. doi: 10.1001/jama.2013.281053</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Lee JJ, Odeh KI, Holcombe SA, Patel RD, Wang SC, Goulet JA, et al. Fat thickness as a risk factor for infection in lumbar spine surgery. Orthopedics. 2016; 39: 1124-1128. doi: 10.3928/01477447-20160819-05</mixed-citation><mixed-citation xml:lang="en">Lee JJ, Odeh KI, Holcombe SA, Patel RD, Wang SC, Goulet JA, et al. Fat thickness as a risk factor for infection in lumbar spine surgery. Orthopedics. 2016; 39: 1124-1128. doi: 10.3928/01477447-20160819-05</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Mehta A, Babu R, Sharma R, Karikari IO, Grunch B, Owens TR, et al. Thickness of subcutaneous fat as a risk factor for infection in cervical spine fusion surgery. J Bone Joint Surg Am. 2013; 95(4): 323-328. doi: 10.2106/JBJS.L.00225</mixed-citation><mixed-citation xml:lang="en">Mehta A, Babu R, Sharma R, Karikari IO, Grunch B, Owens TR, et al. Thickness of subcutaneous fat as a risk factor for infection in cervical spine fusion surgery. J Bone Joint Surg Am. 2013; 95(4): 323-328. doi: 10.2106/JBJS.L.00225</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Watts CD, Houdek MT, Wagner MD, Taunton MJ. Subcutaneous fat thickness is associated with early reoperation and infection after total knee arthroplasty in morbidly obese patients. J Arthroplasty. 2016; 31(8): 1788-1791. doi: 10.1016/j.arth.2016.02.008</mixed-citation><mixed-citation xml:lang="en">Watts CD, Houdek MT, Wagner MD, Taunton MJ. Subcutaneous fat thickness is associated with early reoperation and infection after total knee arthroplasty in morbidly obese patients. J Arthroplasty. 2016; 31(8): 1788-1791. doi: 10.1016/j.arth.2016.02.008</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Marquez-Lara A, Nandyala SV, Sankaranarayanan S, Noureldin M, Singh K. Body mass index as a predictor of complications and mortality after lumbar spine surgery. Spine (Phila Pa 1976). 2014; 39(10): 798-804. doi: 10.1097/BRS.0000000000000232</mixed-citation><mixed-citation xml:lang="en">Marquez-Lara  A, Nandyala  SV, Sankaranarayanan  S, Noureldin M, Singh K. Body mass index as a predictor of complications and mortality after lumbar spine surgery. Spine (Phila Pa 1976). 2014; 39(10): 798-804. doi: 10.1097/BRS.0000000000000232</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Mehta AO, Babu R, Karikari IO, Grunch B, Agarwal VJ, Owens TR, et al. The distribution of body mass as a significant risk factor for lumbar spinal fusion postoperative infections. Spine (Phila Pa 1976). 2012; 37(19): 1652-1656. doi: 10.1097/BRS.0b013e318241b186</mixed-citation><mixed-citation xml:lang="en">Mehta  AO, Babu  R, Karikari  IO, Grunch  B, Agarwal VJ, Owens TR, et  al. The distribution of  body mass as a significant risk factor for lumbar spinal fusion postoperative infections. Spine (Phila Pa 1976). 2012; 37(19): 1652-1656. doi:  10.1097/BRS.0b013e318241b186</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Tan T, Lee H, Huang MS, Rutges J, Marion TE, Mathew J, et al. Prophylactic postoperative measures to minimize surgical site infections in spine surgery: Systematic review and evidence summary. Spine J. 2020; 20(3): 435-447. doi: 10.1016/j.spinee.2019.09.013</mixed-citation><mixed-citation xml:lang="en">Tan T, Lee H, Huang MS, Rutges J, Marion TE, Mathew J, et  al. Prophylactic postoperative measures to minimize surgical site infections in spine surgery: Systematic review and  evidence summary. Spine  J. 2020; 20(3): 435-447. doi:  10.1016/j.spinee.2019.09.013</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Mueller K, Zhao D, Johnson O, Sandhu FA, Voyadzis JM. The difference in surgical site infection rates between open and minimally invasive spine surgery for degenerative lumbar pathology: A retrospective single center experience of 1442 cases. Oper Neurosurg (Hagerstown). 2019; 16(6): 750-755. doi: 10.1093/ons/opy221</mixed-citation><mixed-citation xml:lang="en">Mueller K, Zhao D, Johnson O, Sandhu FA, Voyadzis JM. The difference in surgical site infection rates between open and minimally invasive spine surgery for degenerative lumbar pathology: A retrospective single center experience of 1442 cases. Oper Neurosurg (Hagerstown). 2019; 16(6): 750-755. doi: 10.1093/ons/opy221</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Cottle L, Riordan T. Infectious spondylodiscitis. J Infect. 2008; 56(6): 401-412. doi: 10.1016/j.jinf.2008.02.005</mixed-citation><mixed-citation xml:lang="en">Cottle  L, Riordan T. Infectious spondylodiscitis. J  Infect. 2008; 56(6): 401-412. doi: 10.1016/j.jinf.2008.02.005</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
