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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2023-8.1.10</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-3991</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МОРФОЛОГИЯ, ФИЗИОЛОГИЯ И ПАТОФИЗИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MORPHOLOGY, PHYSIOLOGY AND PATHOPHYSIOLOGY</subject></subj-group></article-categories><title-group><article-title>Изменение реактивности артерий вертебробазилярного бассейна при приёме глюкозо-электролитного напитка с добавлением антиоксидантных растительных экстрактов при  нагрузочном тестировании субмаксимальной мощности</article-title><trans-title-group xml:lang="en"><trans-title>Changes in the reactivity of the vertebrobasilar arteries when using glucose-electrolyte drink with antioxidant plant extracts during submaximal exercise test</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6800-1419</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трибрат</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tribrat</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трибрат Наталья Сергеевна – кандидат биологических наук, доцент кафедры физиологии человека и животных, </p><p>295007, г. Симферополь, пр. Вернадского, 4</p></bio><bio xml:lang="en"><p>Natalia S. Tribrat – Cand.  Sc. (Biol.), Associate Professor at the Department of the Human and Animal Physiology and Biophysics,</p><p>Vernadsky ave. 4, 295007 Simferopol</p></bio><email xlink:type="simple">miu-miu07@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2628-0923</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бирюкова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Birukova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бирюкова Елена Александровна – кандидат биологических наук, доцент кафедры физиологии человека и животных, </p><p>295007, г. Симферополь, пр. Вернадского, 4</p></bio><bio xml:lang="en"><p>Elena  A. Birukova – Cand.  Sc. (Biol.), Associate Professor at the Department of the Human and Animal Physiology and Biophysics, </p><p>Vernadsky ave. 4, 295007 Simferopol</p></bio><email xlink:type="simple">biotema@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0974-6792</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хусаинов</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khusainov</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хусаинов Денис Рашидович – кандидат биологических наук, доцент кафедры физиологии человека и животных, </p><p>295007, г. Симферополь, пр. Вернадского, 4</p></bio><bio xml:lang="en"><p>Denis R. Khusainov – Cand.  Sc. (Biol.), Associate Professor at the Department of the Human and Animal Physiology and Biophysics, </p><p>Vernadsky ave. 4, 295007 Simferopol</p></bio><email xlink:type="simple">gangliu@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4033-1157</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мишин</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Mishin</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мишин Николай Петрович – старший преподаватель кафедры теории и методики физической культуры, </p><p>295007, г. Симферополь, пр. Вернадского, 4</p></bio><bio xml:lang="en"><p>Nikolay P. Mishin – Senior Lecturer at the Department of Theory and Methods of Physical Culture,</p><p>Vernadsky ave. 4, 295007 Simferopol</p></bio><email xlink:type="simple">mishinnick@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0192-1752</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нагаева</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Nagaeva</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нагаева Елена Ивановна – кандидат биологических наук, доцент кафедры теории и методики физической культуры, </p><p>295007, г. Симферополь, пр. Вернадского, 4</p></bio><bio xml:lang="en"><p>Elena I. Nagaeva – Cand. Sc. (Biol.), Associate Professor at the Department of Theory and Methods of Physical Culture,</p><p>Vernadsky ave. 4, 295007 Simferopol</p></bio><email xlink:type="simple">enagaeva75@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5418-7849</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурцева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Burtseva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурцева Елена Владимировна – доцент кафедры фармакологии, </p><p>295007, г. Симферополь, пр. Вернадского, 4</p></bio><bio xml:lang="en"><p>Elena V. Burtseva – Associate Professor at the Department of Pharmacology,</p><p>Vernadsky ave. 4, 295007 Simferopol</p></bio><email xlink:type="simple">burtsevaev2009@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3978-6093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кушнир</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kushnir</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кушнир Cемен Кириллович – студент, </p><p>420012, г. Казань, ул. Бутлерова, 49</p></bio><bio xml:lang="en"><p>Semen K. Kushnir – Student,</p><p>Butlerova str. 49, Kazan 420012</p></bio><email xlink:type="simple">pulpit@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Крымский федеральный университет имени В.И. Вернадского»</institution></aff><aff xml:lang="en"><institution>V.I. Vernadsky Crimean Federal University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Kazan State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>09</day><month>03</month><year>2023</year></pub-date><volume>8</volume><issue>1</issue><fpage>86</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трибрат Н.С., Бирюкова Е.А., Хусаинов Д.Р., Мишин Н.П., Нагаева Е.И., Бурцева Е.В., Кушнир С.К., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Трибрат Н.С., Бирюкова Е.А., Хусаинов Д.Р., Мишин Н.П., Нагаева Е.И., Бурцева Е.В., Кушнир С.К.</copyright-holder><copyright-holder xml:lang="en">Tribrat N.S., Birukova E.A., Khusainov D.R., Mishin N.P., Nagaeva E.I., Burtseva E.V., Kushnir S.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/3991">https://www.actabiomedica.ru/jour/article/view/3991</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Оценка влияния глюкозо-электролитного состава с добавлением растительных экстрактов, обладающих антиоксидантной активностью, на гемодинамические показатели вертебробазилярного бассейна при выполнении ступенчато-возрастающей нагрузки субмаксимальной мощности.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследовании принимали участие 12 спортсменов (6 кандидатов в мастера спорта и 6 мастеров спорта) в возрасте 18–22 лет, занимающихся спортивным ориентированием в среднем 10  лет и более. Испытуемые выполняли ступенчато-возрастающую нагрузку субмаксимальной мощности, а также выполняли нагрузку субмаксимальной мощности с превентивным приёмом глюкозо-электролитного состава с добавлением растительных экстрактов, обладающих антиоксидантными свойствами. Для оценки гемодинамических показателей всем испытуемым проводили ультразвуковую допплерографию сосудов мозга, оценивая показатели кровотока в вертебробазилярном бассейне, а также нагрузочные газовые пробы – в модификации гипо- и гипервентиляции; кроме того, проводили позиционную пробу.</p></sec><sec><title>Результаты</title><p>Результаты. Однократный приём глюкозо-электролитного напитка в условиях нагрузки ступенчато-возрастающей мощности способствовал проявлению гомеостатического эффекта в отношении гемодинамических показателей артерий вертебробазилярного бассейна, о чём свидетельствует приближение к уровню донагрузочных значений максимальной систолической скорости и средней скорости кровотока в пробе с задержкой дыхания, диастолической скорости кровотока – в пробе с гипервентиляцией, показателей индекса пульсации – в торсионной пробе, в отличие от изолированного выполнения нагрузки субмаксимальной мощности, после прохождения которой изменялись как скоростные показатели, так и расчётные индексы в ходе проведения функциональных проб.</p><p>Рассмотрены основные механизмы, лежащие в основе изменения гемодинамических показателей артерий под действием ступенчато-возрастающей нагрузки, а также описаны предполагаемые механизмы, возникающие при комбинированном воздействии ступенчато-возрастающей нагрузки и приёме глюкозо-электролитного состава с добавлением растительных экстрактов, обладающих антиоксидантной активностью.</p></sec><sec><title>Заключение</title><p>Заключение. Показано, что приём глюкозо-электролитного напитка способствовал восстановлению гемодинамических показателей артерий вертебробазилярного бассейна после ступенчато-возрастающей нагрузки субмаксимальной мощности. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>The aim</title><p>The aim. To assess the effect of glucose-electrolyte composition with plant extracts having antioxidant activity on the hemodynamic parameters of vertebrobasilar system during the incrementally increasing submaximal exercise test.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included 12 athletes (6 candidates for master of sports and 6 masters of sports) aged 18–22, who have been engaged in orienteering for 10 years and more. Time of aerobic exercise – 2 hours a day, five days a week. The study subjects performed an incrementally increasing submaximal exercise test and also submaximal exercise test with the preventive intake of a glucose-electrolyte composition with plant extracts having antioxidant properties. To assess the hemodynamic parameters in all study subjects we used Doppler ultrasound of the cerebral vessels, evaluating vertebrobasilar system blood flow, exercise gas test in the modification of hypo- and hyperventilation, and also positional test.</p></sec><sec><title>Results</title><p>Results. A single intake of glucose-electrolyte drink under conditions of incrementally increasing exercise test contributed to the manifestation of a homeostatic effect in hemodynamic parameters of the vertebrobasilar arteries. It is evidenced by the approximation to the pre-exercise level of maximum systolic velocity and average blood velocity in the breath-holding test, of the diastolic blood velocity in the hyperventilation test, and of the pulsatility index in the torsion test, as compared to the isolated submaximal exercise test which caused the change in both velocity indicators and calculated indices during the functional tests.</p><p>The article considers the main mechanisms underlying the change in arterial hemodynamic parameters caused by incrementally increasing load, as well as describes the proposed mechanisms arising from the combined effect of an incrementally increasing load and the intake of a glucose-electrolyte composition with plant extracts having antioxidant activity.</p></sec><sec><title>Conclusion</title><p>Conclusion. It was shown that using glucose-electrolyte drink contributed to the restoration of hemodynamic parameters of the vertebrobasilar arteries after an incrementally increasing submaximal exercise test. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>нагрузочное тестирование субмаксимальной мощности</kwd><kwd>спортсмены</kwd><kwd>глюкозо-электролитный напиток</kwd><kwd>артерии вертебробазилярного бассейна</kwd></kwd-group><kwd-group xml:lang="en"><kwd>incrementally increasing submaximal exercise test</kwd><kwd>athletes</kwd><kwd>glucoseelectrolyte drink</kwd><kwd>vertebrobasilar arteries</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при финансовой поддержке Министерства науки и высшего образования Российской Федерации, программа «Приоритет-2030» № 075- 15-2021-1323.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jarvis SS, Levine BD, Prisk GK, Shykoff BE, Elliott AR, Rosow E, et al. 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