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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2022-7.6.14</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-3890</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ И НЕЙРОХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY AND NEUROSURGERY</subject></subj-group></article-categories><title-group><article-title>Анализ осложнений и неудовлетворительных результатов хирургического лечения дегенеративного стеноза поясничного отдела позвоночного канала у лиц пожилого возраста</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of complications and unsatisfactory results of surgical treatment of degenerative lumbar spinal stenosis in the elderly patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9969-8845</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Очкал</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ochkal</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Очкал Сергей Владимирович – аспирант кафедры травматологии, ортопедии и нейрохирургии </p><p>664049, г. Иркутск, Юбилейный, 100, Россия </p><p> </p></bio><bio xml:lang="en"><p>Sergey V. Ochkal – Postgraduate</p><p>Yubileyniy 100, Irkutsk 664049, Russian Federation </p></bio><email xlink:type="simple">ostin.vl@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9008-6383</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сороковиков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokovikov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сороковиков Владимир Алексеевич – доктор медицинских наук, профессор, директор;  заведующий кафедрой травматологии, ортопедии и нейрохирургии </p><p>664049, г. Иркутск, Юбилейный, 100, Россия </p><p>664003, г. Иркутск, ул. Борцов Революции, 1, Россия </p></bio><bio xml:lang="en"><p>Vladimir A. Sorokovikov – Dr. Sc. (Med.), Professor, Director;  Head of the Department of Traumatology, Orthopedics and Neurosurgery </p><p>Yubileyniy 100, Irkutsk 664049, Russian Federation </p><p> Bortsov Revolyutsii str. 1, Irkutsk 664003, Russian Federation </p></bio><email xlink:type="simple">svladimir10@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9167-637X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапов</surname><given-names>В. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapov</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Потапов Виталий Энгельсович – кандидат медицинских наук, заведующий нейрохирургическим отделением, ведущий научный сотрудник научно-клинического отдела нейрохирургии </p><p>664003, г. Иркутск, ул. Борцов Революции, 1, Россия </p></bio><bio xml:lang="en"><p>Vitaly E. Potapov – Cand. Sc. (Med.), Head of the Neurosurgical Department, Leading Research Officer at the Clinical Research Department of Neurosurgery</p><p>Bortsov Revolyutsii str. 1, Irkutsk 664003, Russian Federation </p></bio><email xlink:type="simple">pva454@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9189-3323</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларионов</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Larionov</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ларионов Сергей Николаевич – доктор медицинских наук, профессор, заведующий научно-клиническим отделом нейрохирургии </p><p>664003, г. Иркутск, ул. Борцов Революции, 1, Россия </p></bio><bio xml:lang="en"><p>Sergey N. Larionov – Dr. Sc. (Med.), Professor, Head of the Clinical Research Department of Neurosurgery </p><p> Bortsov Revolyutsii str. 1, Irkutsk 664003, Russian Federation </p></bio><email xlink:type="simple">snlar@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Иркутская государственная медицинская академия последипломного образования – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuing Professional Education</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Иркутская государственная медицинская академия последипломного образования – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России;&#13;
ФГБНУ «Иркутский научный центр хирургии и травматологии»</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuing Professional Education;&#13;
Irkutsk Scientific Centre of Surgery and Traumatology </institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»</institution></aff><aff xml:lang="en"><institution>Irkutsk Scientific Centre of Surgery and Traumatology</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>29</day><month>12</month><year>2022</year></pub-date><volume>7</volume><issue>6</issue><fpage>137</fpage><lpage>145</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Очкал С.В., Сороковиков В.А., Потапов В.Э., Ларионов С.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Очкал С.В., Сороковиков В.А., Потапов В.Э., Ларионов С.Н.</copyright-holder><copyright-holder xml:lang="en">Ochkal S.V., Sorokovikov V.A., Potapov V.E., Larionov S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/3890">https://www.actabiomedica.ru/jour/article/view/3890</self-uri><abstract><p>Обоснование. Результаты лечения пациентов пожилого возраста, оперированных по поводу стеноза позвоночного канала, позволяют утверждать, что каскад дегенеративных изменений в позвоночно-двигательных сегментах приводит к формированию синдрома смежного уровня, псевдоартроза, а в ряде наблюдений – к нестабильности фиксирующей конструкции.Цель исследования. Определение прогностических факторов возникновения синдрома смежного уровня у пациентов после декомпрессивно-стабилизирующих вмешательств на позвоночнике. Методы. Проведено ретроспективное когортное исследование хирургического лечения 129 больных пожилого возраста (старше 60 лет) за период с января 2018 по март 2022 г., которым выполнено оперативное вмешательство на пояснично-крестцовом уровне по поводу дегенеративного стеноза позвоночного канала.Результаты. Исходы хирургического лечения 129 пациентов и результаты дискриминантного анализа морфометрических исследований данных компьютерной томографии свидетельствуют о том, что наибольшей значимостью развития синдрома смежного уровня обладают показатели угла лордозирования на смежном к оперированному сегменту (среднее значение в анализируемой группе – 12,87 ± 2,22°; в группе контроля – 11,92 ± 2,97°), высоты примыкающего межпозвонкового диска в переднем отделе (среднее значение в анализируемой группе – 12,70 ± 2,44 мм; в группе контроля – 11,46 ± 3,58 мм) и разница высоты диска в передних и задних отделах на смежном уровне (среднее значение в анализируемой группе – 5,48 ± 2,84 мм; в группе контроля – 6,27 ± 2,71 мм).Заключение. При анализе исходов лечения 129 пациентов пожилого возраста, оперированных по поводу дегенеративного стеноза позвоночного канала с выполнением инструментального спондилодеза, выявлено, что у 16 из них развился синдром смежного уровня с увеличением угла лордозирования на смежном к оперированному сегменту уровне. Увеличение высоты примыкающего межпозвонкового диска в переднем отделе и снижение разницы высоты диска в передних и задних отделах на смежном уровне могут рассматриваться как неблагоприятные прогностические факторы (p = 0,83).</p></abstract><trans-abstract xml:lang="en"><p>Background. The results of treatment of the elderly patients operated for spinal stenosis allow us to suggest that a cascade of degenerative changes in the spinal motion segments causes the formation of an adjacent level syndrome, pseudarthrosis, and in some cases – the instability in the fixing structure.The aim of the study. To determine the prognostic factors for the adjacent level syndrome in patients after decompressive and stabilizing spinal surgeries.Methods. We carried out a retrospective cohort study of the surgical treatment of 129 elderly patients (over 60 years of age) for the period from January 2018 to March 2022, who underwent surgery at the lumbosacral level of spine for degenerative spinal stenosis.Results. The outcomes of surgical treatment of 129 patients and the results of discriminant analysis of morphometric studies of computed tomography data indicate that the most significant indicators for the development of the adjacent level syndrome are the lordosis angle in the segment adjacent to the operated one (the mean value in the analyzed group is 12.87 ± 2.22°; in the control group – 11.92 ± 2.97°); the anterior height of the adjacent intervertebral disc (the mean value in the analyzed group is 12.70 ± 2.44 mm; in the control group – 11.46 ± 3.58 mm) and the difference of anterior and posterior disc heights at the adjacent level (the mean value in the analyzed group is 5.48 ± 2.84 mm; in the control group – 6.27 ± 2.71 mm).Conclusion. When analyzing the treatment outcomes of 129 elderly patients operated for degenerative spinal stenosis using instrumented spinal fusion, we revealed that in 16 patients, the adjacent level syndrome developed with an increase in the lordosis angle at the level adjacent to the operated segment. An increase in the anterior height of the adjacent intervertebral disc and the decrease in the difference of anterior and posterior disc heights at the adjacent level can be considered as unfavorable prognostic factors (p = 0.83).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром смежных позвоночных сегментов</kwd><kwd>последствия декомпрессивно-стабилизирующих операций на позвоночнике</kwd><kwd>стеноз позвоночного канала</kwd></kwd-group><kwd-group xml:lang="en"><kwd>adjacent segment syndrome</kwd><kwd>consequences of decompressive and stabilizing spinal surgeries</kwd><kwd>spinal stenosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Халепа Р.В., Климов В.С. Стеноз позвоночного канала поясничного отдела у пациентов пожилого и старческого возраста: состояние проблемы, особенности хирургического лечения. Нейрохирургия. 2017; 1: 100-108.</mixed-citation><mixed-citation xml:lang="en">Khalepa RV, Klimov VS. Lumbar spinal stenosis in elderly and senile patients: problem state and features of surgical treatment. Russian Journal of Neurosurgery. 2017; 1: 100-108. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Балязин В.А., Балязина Е.В. Боль в спине у пожилых людей: особенности лечения. РМЖ. 2016; 24(7): 439-441.</mixed-citation><mixed-citation xml:lang="en">Balyazin VA, Balyazina EV. Back pain in the elderly: Features of treatment. Russian Medical Journal. 2016; 24(7): 439-441. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Machado GC, Ferreira PH, Harris IA, Pinheiro MB, Koes BW, van Tulder M, et al. Effectiveness of surgery for lumbar spinal stenosis: A systematic review and meta-analysis. PLoS One. 2015; 10(3): e0122800. doi: 10.1371/journal.pone.0122800</mixed-citation><mixed-citation xml:lang="en">Machado GC, Ferreira PH, Harris IA, Pinheiro MB, Koes BW, van Tulder M, et al. Effectiveness of surgery for lumbar spinal stenosis: A systematic review and meta-analysis. PLoS One. 2015; 10(3): e0122800. doi: 10.1371/journal.pone.0122800</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Гринь А.А., Никитин А.С., Юсупов С.Э.Р. Хирургическая тактика лечения стеноза позвоночного канала на поясничном уровне у пациентов пожилого и старческого возраста. Нейрохирургия. 2020; 22(1): 93-102.</mixed-citation><mixed-citation xml:lang="en">Grin AA, Nikitin АS, Yusupov SR. Surgical treatment of spinal canal stenosis at the lumbar level in the elderly and senile patients. Russian Journal of Neurosurgery. 2020; 22(1): 93-102. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lurie J, Tomkins-Lane C. Management of lumbar spinal stenosis. BMJ. 2016; 352: h6234. doi: 10.1136/bmj.h6234</mixed-citation><mixed-citation xml:lang="en">Lurie J, Tomkins-Lane C. Management of lumbar spinal stenosis. BMJ. 2016; 352: h6234. doi: 10.1136/bmj.h6234</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Covaro A, Vilà-Canet G, de Frutos AG, Ubierna MT, Ciccolo F, Caceres E. Management of degenerative lumbar spinal stenosis: An evidence-based review. EFORT Open Rev. 2017; 1(7): 267-274. doi: 10.1302/2058-5241.1.000030</mixed-citation><mixed-citation xml:lang="en">Covaro A, Vilà-Canet G, de Frutos AG, Ubierna MT, Ciccolo F, Caceres E. Management of degenerative lumbar spinal stenosis: An evidence-based review. EFORT Open Rev. 2017; 1(7): 267-274. doi: 10.1302/2058-5241.1.000030</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Machado GC, Ferreira PH, Yoo RI, Harris IA, Pinheiro MB, Koes BW, et al. Surgical options for lumbar spinal stenosis. Cochrane Database Syst Rev. 2016; 11(11): CD012421. doi: 10.1002/14651858.CD012421</mixed-citation><mixed-citation xml:lang="en">Machado GC, Ferreira PH, Yoo RI, Harris IA, Pinheiro MB, Koes BW, et al. Surgical options for lumbar spinal stenosis. Cochrane Database Syst Rev. 2016; 11(11): CD012421. doi: 10.1002/14651858.CD012421</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kalff R, Ewald C, Waschke A, Gobisch L, Hopf C. Degenerative lumbar spinal stenosis in older people: Current treatment options. Dtsch Arztebl Int. 2013; 110(37): 613-624. doi: 10.3238/arztebl.2013.0613</mixed-citation><mixed-citation xml:lang="en">Kalff R, Ewald C, Waschke A, Gobisch L, Hopf C. Degenerative lumbar spinal stenosis in older people: Current treatment options. Dtsch Arztebl Int. 2013; 110(37): 613-624. doi: 10.3238/arztebl.2013.0613</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao X, Du L, Xie Y, Zhao J. Effect of lumbar lordosis on the adjacent segment in transforaminal lumbar interbody fusion: A finite element analysis. World Neurosurg. 2018; 114: e114-e120. doi: 10.1016/j.wneu.2018.02.073</mixed-citation><mixed-citation xml:lang="en">Zhao X, Du L, Xie Y, Zhao J. Effect of lumbar lordosis on the adjacent segment in transforaminal lumbar interbody fusion: A finite element analysis. World Neurosurg. 2018; 114: e114-e120. doi: 10.1016/j.wneu.2018.02.073</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Park P, Garton HJ, Gala VC, Hoff JT, McGillicuddy JE. Adjacent segment disease after lumbar or lumbosacral fusion: Review of the literature. Spine (Phila Pa 1976). 2004; 29(17): 1938-1944. doi: 10.1097/01.brs.0000137069.88904.03</mixed-citation><mixed-citation xml:lang="en">Park P, Garton HJ, Gala VC, Hoff JT, McGillicuddy JE. Adjacent segment disease after lumbar or lumbosacral fusion: Review of the literature. Spine (Phila Pa 1976). 2004; 29(17): 1938-1944. doi: 10.1097/01.brs.0000137069.88904.03</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Chen BL, Wei FX, Ueyama K, Xie DH, Sannohe A, Liu SY. Adjacent segment degeneration after single-segment PLIF: The risk factor for degeneration and its impact on clinical outcomes. Eur Spine J. 2011; 20(11): 1946-1950. doi: 10.1007/s00586-011-1888-1</mixed-citation><mixed-citation xml:lang="en">Chen BL, Wei FX, Ueyama K, Xie DH, Sannohe A, Liu SY. Adjacent segment degeneration after single-segment PLIF: The risk factor for degeneration and its impact on clinical outcomes. Eur Spine J. 2011; 20(11): 1946-1950. doi: 10.1007/s00586-011-1888-1</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Liang J, Dong Y, Zhao H. Risk factors for predicting symptomatic adjacent segment degeneration requiring surgery in patients after posterior lumbar fusion. J Orthop Surg Res. 2014; 9(1): 1-6. doi: 10.1186/s13018-014-0097-0</mixed-citation><mixed-citation xml:lang="en">Liang J, Dong Y, Zhao H. Risk factors for predicting symptomatic adjacent segment degeneration requiring surgery in patients after posterior lumbar fusion. J Orthop Surg Res. 2014; 9(1): 1-6. doi: 10.1186/s13018-014-0097-0</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ma Z, Huang S, Sun J, Li F, Sun J, Pi G. Risk factors for upper adjacent segment degeneration after multi-level posterior lumbar spinal fusion surgery. J Orthop Surg Res. 2019; 14(1): 89. doi: 10.1186/s13018-019-1126-9</mixed-citation><mixed-citation xml:lang="en">Ma Z, Huang S, Sun J, Li F, Sun J, Pi G. Risk factors for upper adjacent segment degeneration after multi-level posterior lumbar spinal fusion surgery. J Orthop Surg Res. 2019; 14(1): 89. doi: 10.1186/s13018-019-1126-9</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Sears WR, Sergides IG, Kazemi N, Smith M, White GJ, Osburg B. Incidence and prevalence of surgery at segments adjacent to a previous posterior lumbar arthrodesis. Spine J. 2011; 11(1): 11-20. doi: 10.1016/j.spinee.2010.09.026</mixed-citation><mixed-citation xml:lang="en">Sears WR, Sergides IG, Kazemi N, Smith M, White GJ, Osburg B. Incidence and prevalence of surgery at segments adjacent to a previous posterior lumbar arthrodesis. Spine J. 2011; 11(1): 11-20. doi: 10.1016/j.spinee.2010.09.026</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Axelsson P, Johnsson R, Strömqvist B. Adjacent segment hypermobility after lumbar spine fusion: No association with progressive degeneration of the segment 5 years after surgery. Acta Orthop. 2007; 78(6): 834-839. doi: 10.1080/17453670710014635</mixed-citation><mixed-citation xml:lang="en">Axelsson P, Johnsson R, Strömqvist B. Adjacent segment hypermobility after lumbar spine fusion: No association with progressive degeneration of the segment 5 years after surgery. Acta Orthop. 2007; 78(6): 834-839. doi: 10.1080/17453670710014635</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Cao L, Liu Y, Mei W, Xu J, Zhan S. Biomechanical changes of degenerated adjacent segment and intact lumbar spine after lumbosacral topping-off surgery: A three-dimensional finite element analysis. BMC Musculoskelet Disord. 2020; 21(1): 104. doi: 10.1186/s12891-020-3128-5</mixed-citation><mixed-citation xml:lang="en">Cao L, Liu Y, Mei W, Xu J, Zhan S. Biomechanical changes of degenerated adjacent segment and intact lumbar spine after lumbosacral topping-off surgery: A three-dimensional finite element analysis. BMC Musculoskelet Disord. 2020; 21(1): 104. doi: 10.1186/s12891-020-3128-5</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ghasemi AA. Adjacent segment degeneration after posterior lumbar fusion: An analysis of possible risk factors. Clin Neurol Neurosurg. 2016; 143: 15-18. doi: 10.1016/j.clineuro.2016.02.004</mixed-citation><mixed-citation xml:lang="en">Ghasemi AA. Adjacent segment degeneration after posterior lumbar fusion: An analysis of possible risk factors. Clin Neurol Neurosurg. 2016; 143: 15-18. doi: 10.1016/j.clineuro.2016.02.004</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Adogwa O, Carr RK, Kudyba K, Karikari I, Bagley CA, Gokaslan ZL, et al. Revision lumbar surgery in elderly patients with symptomatic pseudarthrosis, adjacent-segment disease, or same-level recurrent stenosis. Part 1. Two-year outcomes and clinical efficacy: Clinical article. J Neurosurg Spine. 2013; 18(2): 139-146. doi: 10.3171/2012.11.SPINE12224</mixed-citation><mixed-citation xml:lang="en">Adogwa O, Carr RK, Kudyba K, Karikari I, Bagley CA, Gokaslan ZL, et al. Revision lumbar surgery in elderly patients with symptomatic pseudarthrosis, adjacent-segment disease, or same-level recurrent stenosis. Part 1. Two-year outcomes and clinical efficacy: Clinical article. J Neurosurg Spine. 2013; 18(2): 139-146. doi: 10.3171/2012.11.SPINE12224</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Kaner T, Ozer AF. Dynamic stabilization for challenging lumbar degenerative diseases of the spine: A review of the literature. Adv Orthop. 2013; 2013: 753470. doi: 10.1155/2013/753470</mixed-citation><mixed-citation xml:lang="en">Kaner T, Ozer AF. Dynamic stabilization for challenging lumbar degenerative diseases of the spine: A review of the literature. Adv Orthop. 2013; 2013: 753470. doi: 10.1155/2013/753470</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou ZJ, Xia P, Zhao X, Fang XQ, Zhao FD, Fan SW. Can posterior dynamic stabilization reduce the risk of adjacent segment deterioration? Turk Neurosurg. 2013; 23(5): 579-589. doi: 10.5137/1019-5149.JTN.6573-12.1</mixed-citation><mixed-citation xml:lang="en">Zhou ZJ, Xia P, Zhao X, Fang XQ, Zhao FD, Fan SW. Can posterior dynamic stabilization reduce the risk of adjacent segment deterioration? Turk Neurosurg. 2013; 23(5): 579-589. doi: 10.5137/1019-5149.JTN.6573-12.1</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Lu K, Liliang PC, Wang HK, Liang CL, Chen JS, Chen TB, et al. Reduction in adjacent-segment degeneration after multilevel posterior lumbar interbody fusion with proximal DIAM implantation. J Neurosurg Spine. 2015; 23(2): 190-196. doi: 10.3171/2014.12.SPINE14666</mixed-citation><mixed-citation xml:lang="en">Lu K, Liliang PC, Wang HK, Liang CL, Chen JS, Chen TB, et al. Reduction in adjacent-segment degeneration after multilevel posterior lumbar interbody fusion with proximal DIAM implantation. J Neurosurg Spine. 2015; 23(2): 190-196. doi: 10.3171/2014.12.SPINE14666</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Lee CH, Kim YE, Lee HJ, Kim DG, Kim CH. Biomechanical effects of hybrid stabilization on the risk of proximal adjacentsegment degeneration following lumbar spinal fusion using an interspinous device or a pedicle screw-based dynamic fixator. J Neurosurg Spine. 2017; 27(6): 643-649. doi: 10.3171/2017.3.SPINE161169</mixed-citation><mixed-citation xml:lang="en">Lee CH, Kim YE, Lee HJ, Kim DG, Kim CH. Biomechanical effects of hybrid stabilization on the risk of proximal adjacentsegment degeneration following lumbar spinal fusion using an interspinous device or a pedicle screw-based dynamic fixator. J Neurosurg Spine. 2017; 27(6): 643-649. doi: 10.3171/2017.3.SPINE161169</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lee CH, Hyun SJ, Kim KJ, Jahng TA, Yoon SH, Kim HJ. The efficacy of lumbar hybrid stabilization using the DIAM to delay adjacent segment degeneration: An intervention comparison study with a minimum 2-year follow-up. Neurosurgery. 2013; 73(Suppl 2): ons224-ons232. doi: 10.1227/NEU.0b013e31828e8ddc</mixed-citation><mixed-citation xml:lang="en">Lee CH, Hyun SJ, Kim KJ, Jahng TA, Yoon SH, Kim HJ. The efficacy of lumbar hybrid stabilization using the DIAM to delay adjacent segment degeneration: An intervention comparison study with a minimum 2-year follow-up. Neurosurgery. 2013; 73(Suppl 2): ons224-ons232. doi: 10.1227/NEU.0b013e31828e8ddc</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Wang H, Peng J, Zeng Q, Zhong Y, Xiao C, Ye Y, et al. Dynesys system vs posterior decompression and fusion for the treatment of lumbar degenerative diseases. Medicine (Baltimore). 2020; 99(21): e19784. doi: 10.1097/MD.0000000000019784</mixed-citation><mixed-citation xml:lang="en">Wang H, Peng J, Zeng Q, Zhong Y, Xiao C, Ye Y, et al. Dynesys system vs posterior decompression and fusion for the treatment of lumbar degenerative diseases. Medicine (Baltimore). 2020; 99(21): e19784. doi: 10.1097/MD.0000000000019784</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Kuo CH, Huang WC, Wu JC, Tu TH, Fay LY, Wu CL, et al. Radiological adjacent-segment degeneration in L4–5 spondylolisthesis: comparison between dynamic stabilization and minimally invasive transforaminal lumbar interbody fusion. J Neurosurg Spine. 2018; 29(3): 250-258. doi: 10.3171/2018.1.SPINE17993</mixed-citation><mixed-citation xml:lang="en">Kuo CH, Huang WC, Wu JC, Tu TH, Fay LY, Wu CL, et al. Radiological adjacent-segment degeneration in L4–5 spondylolisthesis: comparison between dynamic stabilization and minimally invasive transforaminal lumbar interbody fusion. J Neurosurg Spine. 2018; 29(3): 250-258. doi: 10.3171/2018.1.SPINE17993</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hu A, Sun C, Liang Y, Wang H, Li X, Dong J. Multi-segmental lumbar spinal stenosis treated with Dynesys stabilization versus lumbar fusion in elderly patients: A retrospective study with a minimum of 5 years’ follow-up. Arch Orthop Trauma Surg. 2019; 139(10): 1361-1368. doi: 10.1007/s00402-019-03234-3</mixed-citation><mixed-citation xml:lang="en">Hu A, Sun C, Liang Y, Wang H, Li X, Dong J. Multi-segmental lumbar spinal stenosis treated with Dynesys stabilization versus lumbar fusion in elderly patients: A retrospective study with a minimum of 5 years’ follow-up. Arch Orthop Trauma Surg. 2019; 139(10): 1361-1368. doi: 10.1007/s00402-019-03234-3</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Tsuang FY, Tsai JC, Lai DM. Effect of lordosis on adjacent levels after lumbar interbody fusion, before and after removal of the spinal fixator: A finite element analysis. BMC Musculoskelet Dis. 2019; 20(1): 470. doi: 10.1186/s12891-019-2886-4</mixed-citation><mixed-citation xml:lang="en">Tsuang FY, Tsai JC, Lai DM. Effect of lordosis on adjacent levels after lumbar interbody fusion, before and after removal of the spinal fixator: A finite element analysis. BMC Musculoskelet Dis. 2019; 20(1): 470. doi: 10.1186/s12891-019-2886-4</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou C, Cha T, Li G. An upper bound computational model for investigation of fusion effects on adjacent segment biomechanics of the lumbar spine. Comput Methods Biomech Biomed Engin. 2019; 22(14): 1126-1134. doi: 10.1080/10255842.2019.1639047</mixed-citation><mixed-citation xml:lang="en">Zhou C, Cha T, Li G. An upper bound computational model for investigation of fusion effects on adjacent segment biomechanics of the lumbar spine. Comput Methods Biomech Biomed Engin. 2019; 22(14): 1126-1134. doi: 10.1080/10255842.2019.1639047</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Jiang S, Li W. Biomechanical study of proximal adjacent segment degeneration after posterior lumbar interbody fusion and fixation: A finite element analysis. J Orthop Surg Res. 2019; 14(1): 135. doi: 10.1186/s13018-019-1150-9</mixed-citation><mixed-citation xml:lang="en">Jiang S, Li W. Biomechanical study of proximal adjacent segment degeneration after posterior lumbar interbody fusion and fixation: A finite element analysis. J Orthop Surg Res. 2019; 14(1): 135. doi: 10.1186/s13018-019-1150-9</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bieri KS, Goodwin K, Aghayev E, Riesner HJ, GreinerPerth R. Dynamic posterior stabilization versus posterior lumbar intervertebral fusion: A matched cohort study based on the Spine Tango Registry. J Neurol Surg A Cent Eur Neurosurg. 2018; 79(3): 224-230. doi: 10.1055/s-0037-1615264</mixed-citation><mixed-citation xml:lang="en">Bieri KS, Goodwin K, Aghayev E, Riesner HJ, GreinerPerth R. Dynamic posterior stabilization versus posterior lumbar intervertebral fusion: A matched cohort study based on the Spine Tango Registry. J Neurol Surg A Cent Eur Neurosurg. 2018; 79(3): 224-230. doi: 10.1055/s-0037-1615264</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
