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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2022-7.4.20</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-3658</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGERY</subject></subj-group></article-categories><title-group><article-title>Случай успешного многоэтапного хирургического лечения осложнённого эхинококкоза обеих долей печени</article-title><trans-title-group xml:lang="en"><trans-title>A case of successful multi-stage surgical treatment of liver echinococcosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7617-6422</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Краснов</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasnov</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Краснов Аркадий Олегович – кандидат медицинских наук, врач-хирург хирургического отделения № 2 </p><p>650000, г. Кемерово, ул. Островского, 22</p></bio><bio xml:lang="en"><p>Arkadiy O. Krasnov – Cand. Sc. (Med.), Surgeon of the Surgical Department No. 2</p><p>Ostrovskogo str. 22, Kemerovo 650000</p></bio><email xlink:type="simple">aokrasnov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1178-5205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анищенко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anishchenko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анищенко Владимир Владимирович – доктор медицинских наук, профессор, заведующий кафедрой хирургии факультета усовершенствования врачей, ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России; главный специалист по хирургии, Клинический госпиталь «Авиценна» группы компаний «Мать и дитя»</p><p>630091, г. Новосибирск, Красный просп., 52; 630099, г. Новосибирск, ул. Коммунистическая, 17/1</p><p> </p></bio><bio xml:lang="en"><p>Vladimir V. Anishchenko – Dr. Sc. (Med.), Professor, Head of the Department of Surgery, Faculty of Postgraduate Medical Education, Novosibirsk State Medical University; Chief Specialist in Surgery, Avicenna Clinical Hospital of the Mother and Child Group of Companies</p><p>Krasny prospect 52, Novosibirsk 630091; Kommunisticheskaya str. 17/1, Novosibirsk 630099</p></bio><email xlink:type="simple">avv1110@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2216-1545</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пачгин</surname><given-names>И. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Pachgin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пачгин Игорь Вадимович – кандидат медицинских наук, главный врач</p><p>650000, г. Кемерово, ул. Островского, 22</p></bio><bio xml:lang="en"><p>Igor V. Pachgin – Cand. Sc. (Med.), Chief Physician</p><p>Ostrovskogo str. 22, Kemerovo 650000</p></bio><email xlink:type="simple">pachgin@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9262-3656</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Краснов</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasnov</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Краснов Константин Аркадьевич – кандидат медицинских наук, заместитель главного врача по хирургии и трансплантологической помощи, ГАУЗ «Кузбасская клиническая больница скорой помощи им. М.А. Подгорбунского»; доцент кафедры госпитальной хирургии, ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России</p><p>650000, г. Кемерово, ул. Островского, 22;  650056, г. Кемерово, ул. Ворошилова, 22а</p></bio><bio xml:lang="en"><p> Konstantin A. Krasnov – Cand. Sc. (Med.), Deputy Chief Physician for Surgery and Transplant Care, Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsky; Associate Professor at the Department of Hospital Surgery, Kemerovo State Medical University</p><p>Ostrovskogo str. 22, Kemerovo 650000; Voroshilova str. 22a, Kemerovo 650056</p></bio><email xlink:type="simple">krasnov8k@rambler.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8230-6676</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пельц</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pelz</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пельц Владислав Александрович – кандидат медицинских наук, заведующий хирургическим отделением № 2, ГАУЗ «Кузбасская клиническая больница скорой помощи им. М.А. Подгорбунского»; доцент кафедры госпитальной хирургии, ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России</p><p>650000, г. Кемерово, ул. Островского, 22; 650056, г. Кемерово, ул. Ворошилова, 22а</p><p> </p></bio><bio xml:lang="en"><p>Vladislav A. Pelz – Cand. Sc. (Med.), Head of the Surgical Department No. 2, Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsky; Associate Professor at the Department of Hospital Surgery, Kemerovo State Medical University</p><p>Ostrovskogo str. 22, Kemerovo 650000; Voroshilova str. 22a, Kemerovo 650056</p></bio><email xlink:type="simple">vpelc_c1@rambler.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5214-7771</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Краснов</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasnov</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Краснов Олег Аркадьевич – доктор медицинских наук, профессор кафедры факультетской хирургии, ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России; заведующий поликлиникой № 1, ГАУЗ «Клинический консультативный диагностический центр им. И.А. Колпинского»</p></bio><bio xml:lang="en"><p>Oleg A. Krasnov – Dr. Sc. (Med.), Professor at the Faculty Surgery Department, Kemerovo State Medical University; Head of Polyclinic N 1, Clinical Consultative Diagnostic Center named after I.A. Kolpinsky</p><p>Voroshilova str. 22a, Kemerovo 650056, LLeningradskiy ave. 49, Kemerovo 650003</p></bio><email xlink:type="simple">xo1@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9439-2049</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павленко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlenko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павленко Владимир Вячеславович – доктор медицинских наук, профессор, заведующий кафедрой госпитальной хирургии, ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России; заместитель главного врача по научной деятельности, ГАУЗ «Кузбасская клиническая больница скорой помощи им. М.А. Подгорбунского»</p><p>650056, г. Кемерово, ул. Ворошилова, 22а; 650000, г. Кемерово, ул. Островского, 22</p><p> </p></bio><bio xml:lang="en"><p>Vladimir V. Pavlenko – Dr. Sc. (Med.), Head of the Department of Hospital Surgery, Kemerovo State Medical University; Deputy Chief Physician for Scientific Activities, Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsky</p><p>Voroshilova str. 22a, Kemerovo 650056; Ostrovskogo str. 22, Kemerovo 650000</p></bio><email xlink:type="simple">pavlenkovv@list.ru</email><xref ref-type="aff" rid="aff-6"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГАУЗ «Кузбасская клиническая больница скорой помощи им. М.А. Подгорбунского»</institution></aff><aff xml:lang="en"><institution>Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsk</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России; &#13;
Клинический госпиталь «Авиценна» группы компаний «Мать и дитя»</institution></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University; &#13;
Avicenna Clinical Hospital of the Mother and Child Group of Companies</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГАУЗ «Кузбасская клиническая больница скорой помощи им. М.А. Подгорбунского»</institution></aff><aff xml:lang="en"><institution>Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsky</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГАУЗ «Кузбасская клиническая больница скорой помощи им. М.А. Подгорбунского»; &#13;
ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsky; &#13;
Kemerovo State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России; &#13;
ГАУЗ «Клинический консультативный диагностический центр им. И.А. Колпинского»</institution></aff><aff xml:lang="en"><institution>Kemerovo State Medical University; &#13;
Clinical Consultative Diagnostic Center named after I.A. Kolpinsky</institution></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России; &#13;
ГАУЗ «Кузбасская клиническая больница скорой помощи им. М.А. Подгорбунского»</institution></aff><aff xml:lang="en"><institution>Kemerovo State Medical University; &#13;
Kuzbass Clinical Emergency Hospital named after M.A. Podgorbunsky</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2022</year></pub-date><volume>7</volume><issue>4</issue><fpage>174</fpage><lpage>180</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Краснов А.О., Анищенко В.В., Пачгин И.B., Краснов К.А., Пельц В.А., Краснов О.А., Павленко В.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Краснов А.О., Анищенко В.В., Пачгин И.B., Краснов К.А., Пельц В.А., Краснов О.А., Павленко В.В.</copyright-holder><copyright-holder xml:lang="en">Krasnov A.O., Anishchenko V.V., Pachgin I.V., Krasnov K.A., Pelz V.A., Krasnov O.A., Pavlenko V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/3658">https://www.actabiomedica.ru/jour/article/view/3658</self-uri><abstract><p>Представлен клинический случай успешного радикального многоэтапного хирургического лечения пациентки с билобарным паразитарным поражением печени эхинококкозом, осложнённым инфицированием одной из кист. Пациентка поступила в клинику с объёмными образованиями обеих долей печени. На этапе дифференциальной диагностики на основании верификации процесса путём пункционной биопсии под ультразвуковым контролем достоверно установлена этиология объёмных образований. На этапе первичного стационарного этапа диагностировано инфицирование одной из эхинококковых кист, по поводу чего выполнено дренирование кисты под ультразвуковым контролем. После пациентка была выписана на амбулаторный этап для компенсации, коррекции общего уровня здоровья и нутритивного статуса. На следующем этапе стационарного обследования у пациентки определён недостаточный уровень функциональных резервов печени для выполнения радикальной операции. По этой причине было выполнено лапароскопическое лигирование правой ветви воротной вены с целью развития викарной гипертрофии контрлатеральной доли. Через 30 суток возросший уровень функциональных резервов печени позволил планировать радикальное хирургическое лечение с допустимым риском для пациентки. Была выполнена операция в объёме правосторонней расширенной гемигепатэктомии с краевой резекцией 3-го сегмента печени. Явления печёночной недостаточности в послеоперационном периоде по шкале ISGLS были расценены как Grade А. Пациентка была выписана из стационара в удовлетворительном состоянии на 10-е сутки после операции. В послеоперационном периоде назначены курсы терапии альбендазолом по стандартной схеме. Пациентка находится под наблюдением более года после лечения. Состояние удовлетворительное. Рецидива заболевания не отмечено.</p></abstract><trans-abstract xml:lang="en"><p>A clinical case of successful radical multi-stage surgical treatment of a patient with bilobar parasitic lesion of the liver with echinococcosis complicated by infection of one of the cysts is presented. The patient was admitted to the clinic with volumetric lesions in both lobes of the liver. At the stage of differential diagnosis, on the basis of process verification by puncture biopsy under ultrasound control, the ethiology of mass lesions was reliably established. At the primary stationary stage, infection of one of the echinococcal cysts was diagnosed, for which the cyst was drained under ultrasound control. After that, the patient was discharged to the outpatient care for compensation, correction of the general level of health and nutritional status. At the next stage of the inpatient examination, the patient was determined to have an insufficient level of functional reserves of the liver to perform a radical operation. For this reason, laparoscopic ligation of the right branch of the portal vein was performed in order to develop vicarious hypertrophy of the contralateral lobe. After 30 days, the increased level of functional reserves of the liver made it possible to plan radical surgical treatment with an acceptable risk for the patient. The operation was performed in the amount of right-sided extended hemihepatectomy with marginal resection of the 3rd segment of the liver. The symptoms of liver failure in the postoperative period according to the ISGLS scale were regarded as Grade A. The patient was discharged from the hospital in a satisfactory condition on day 10 after the operation. In the postoperative period, courses of therapy with albendazole were prescribed according to the standard scheme. The patient is under observation for more than a year after treatment. The condition is satisfactory. No recurrence of the disease was noted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эхинококкоз печени</kwd><kwd>диагностический алгоритм</kwd><kwd>этапное хирургическое лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver echinococcosis</kwd><kwd>diagnostic algorithm</kwd><kwd>staged surgical treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Singh U, Kumar S, Gour H, Singh N, Ramaraj M, Mittal V, et al. Complicated hydatid cyst and «air bubble» sign: A steppingstone to correct diagnosis. Am J Case Rep. 2015; 18(16): 20-24. doi: 10.12659/AJCR.892621</mixed-citation><mixed-citation xml:lang="en">Singh U, Kumar S, Gour H, Singh N, Ramaraj M, Mittal V, et al. Complicated hydatid cyst and «air bubble» sign: A steppingstone to correct diagnosis. 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