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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2022-7.4.19</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-3657</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТРАВМАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>TRAUMATOLOGY</subject></subj-group></article-categories><title-group><article-title>Сложность выбора метода обезболивания после тотального эндопротезирования крупных суставов нижней конечности (случай из практики, обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>The difficulty of choosing the method of analgesia after total replacement of the lower limb large joints (case report, literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7602-6720</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедь</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebed</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедь Максим Леонидович – доктор медицинских наук, заведующий отделением анестезиологии-реанимации, ФГБНУ «Иркутский научный центр хирургии и травматологии»; ассистент кафедры анестезиологии-реаниматологии, ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России</p><p>664003, г. Иркутск, ул. Борцов Революции, 1; 664003, г. Иркутск, ул. Красного Восстания, 1</p></bio><bio xml:lang="en"><p>Maksim L. Lebed – Dr. Sc. (Med.), Head of the Department of Anesthesiology and Intensive Care, Irkutsk Scientific Centre of Surgery and Traumatology; Teaching Assistant at the Department of Anesthesiology and Resuscitation, Irkutsk State Medical University</p><p>Bortsov Revolyutsii str. 1, Irkutsk 664003; Krasnogo Vosstaniya str. 1, Irkutsk 664003</p><p> </p></bio><email xlink:type="simple">swanmax@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7755-3397</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кирпиченко</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirpichenko</surname><given-names>M. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кирпиченко Михаил Геннадьевич – кандидат медицинских наук, врач отделения анестезиологии-реанимации</p><p>664003, г. Иркутск, ул. Борцов Революции, 1</p></bio><bio xml:lang="en"><p>Mikhail G. Kirpichenko – Cand. Sc. (Med.), Physician at the Department of Anesthesiology and Intensive Care</p><p>Bortsov Revolyutsii str. 1, Irkutsk 664003</p></bio><email xlink:type="simple">kirpnet@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7545-4419</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyev</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильев Вячеслав Юрьевич – заведующий травматолого-ортопедическим отделением № 2</p><p>664003, г. Иркутск, ул. Борцов Революции, 1</p></bio><bio xml:lang="en"><p>Vyacheslav Yu. Vasilyev – Head of the Department of Traumatology and Orthopedics No. 2</p><p>Bortsov Revolyutsii str. 1, Irkutsk 664003</p></bio><email xlink:type="simple">coxa_vara@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голуб</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Golub</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Голуб Игорь Ефимович – доктор медицинских наук, профессор кафедры анестезиологии-реаниматологии</p><p>664003, г. Иркутск, ул. Красного Восстания, 1</p></bio><bio xml:lang="en"><p>Igor E. Golub – Dr. Sc. (Med.), Professor at the Department of Anesthesiology and Resuscitation</p><p>Krasnogo Vosstaniya str. 1, Irkutsk 664003</p></bio><email xlink:type="simple">i.golub@ismu.baikal.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»; &#13;
ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk Scientific Centre of Surgery and Traumatology; &#13;
Irkutsk state Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»</institution></aff><aff xml:lang="en"><institution>Irkutsk Scientific Centre of Surgery and Traumatology</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk state Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2022</year></pub-date><volume>7</volume><issue>4</issue><fpage>164</fpage><lpage>173</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лебедь М.Л., Кирпиченко М.Г., Васильев В.Ю., Голуб И.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Лебедь М.Л., Кирпиченко М.Г., Васильев В.Ю., Голуб И.Е.</copyright-holder><copyright-holder xml:lang="en">Lebed M.L., Kirpichenko M.G., Vasilyev V.V., Golub I.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/3657">https://www.actabiomedica.ru/jour/article/view/3657</self-uri><abstract><p>Описан случай успешного лечения пациентки с перипротезным переломом бедренной кости, произошедшим через сутки после тотального эндопротезирования тазобедренного сустава в результате падения, возможно, связанного с послеоперационной проводниковой анальгезией. Эндопротезирование крупных суставов нижней конечности уже в нынешнем десятилетии может стать наиболее часто выполняемым видом планового хирургического вмешательства, объективной предпосылкой чему является всё более широкая распространённость остеопороза, остеоартрита, ревматоидных заболеваний и переломов бедра. Несмотря на все усилия, проблема контроля послеоперационной боли при этих вмешательствах в настоящее время остаётся нерешённой. «Золотого стандарта» обезболивания при тотальном эндопротезировании тазобедренного сустава и коленного сустава в настоящее время не существует. Отличное соотношение эффективности и безопасности демонстрируют программы мультимодального обезболивания на основе блокад периферических нервов. Однако, обладая несомненными преимуществами, проводниковая анестезия/анальгезия имеет критически важный недостаток. Краеугольным камнем послеоперационной реабилитации пациентов, перенёсших тотальное эндопротезирование тазобедренного или коленного суставов, является ранняя активизация. А все методы проводниковой анестезии ассоциируются с двигательной блокадой. В частности, блокада бедренного нерва вызывает слабость четырёхглавой мышцы бедра, провоцируя непреднамеренное падение пациентов при попытке встать или пойти. Ситуацию с выбором метода обезболивания после эндопротезирования крупных суставов нижней конечности можно охарактеризовать словами: «предстоит пройти ещё долгий путь».</p></abstract><trans-abstract xml:lang="en"><p>A case of successful treatment of a patient with a periprosthetic fracture of the femur is described. The fracture occurred one day after total hip replacement as a result of a fall, possibly associated with postoperative conduction analgesia. Lower limb large joints total replacement may become the most frequently performed type of elective surgery already in the current decade. The increasing prevalence of osteoporosis, osteoarthritis, rheumatic diseases and hip fractures is an objective prerequisite for it. Despite of all efforts, the problem of postoperative pain control during these surgical interventions currently remains unresolved. There is currently no “gold standard” for pain relief after total hip and knee replacement surgeries. An excellent ratio of effectiveness and safety is demonstrated by multimodal pain relief programs based on peripheral nerve blocks. However, while having undeniable advantages, conduction anesthesia/analgesia has a critically important drawback. The cornerstone of postoperative rehabilitation for patients undergoing total hip or knee replacement is their early activation. All methods of conduction anesthesia are associated with motor blockade. In particular, femoral nerve block causes weakness of quadriceps muscle of thigh, inducing patients’ inadvertent falling when attempting to stand or walk. The situation with the choice of the method of anesthesia after total replacement of the lower limb large joints can be described as “a long way to go”.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>перипротезный перелом</kwd><kwd>тотальное эндопротезирование тазобедренного сустава</kwd><kwd>блокада бедренного нерва</kwd><kwd>двигательная блокада</kwd><kwd>ранняя активизация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>periprosthetic fracture</kwd><kwd>total hip replacement</kwd><kwd>femoral nerve block</kwd><kwd>motor blockade</kwd><kwd>early mobilization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mondanelli N, Troiano E, Facchini A, Ghezzi R, Di Meglio M, Nuvoli N, et al. 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