actabiomedicaActa Biomedica ScientificaActa Biomedica Scientifica2541-94202587-9596Scientific Centre for Family Health and Human Reproduction Problems10.29413/ABS.2022-7.2.16actabiomedica-3434Research ArticleОФТАЛЬМОЛОГИЯOPHTHALMOLOGYОптическая когерентная томография в диагностике и мониторинге врождённой и ювенильной глаукомыOptical coherence tomography in the diagnosis and monitoring of congenital and juvenile glaucomahttps://orcid.org/0000-0002-0227-7682ЖуковаС. И.ZhukovaS. I.

кандидат медицинских наук, заведующая диагностическим отделением, врач-офтальмолог

664033, г. Иркутск, ул. Лермонтова, 337

Cand. Sc. (Med.), Head of the Diagnostic Department, Ophthalmologist

Lermontova str. 337, Irkutsk 664033

zhukswetlana@yandex.ruhttps://orcid.org/0000-0003-0547-7521ЮрьеваТ. Н.IurevaT. N.

доктор медицинских наук, профессор, заместитель директора по научной работе; профессор кафедры офтальмологии; профессор кафедры глазных болезней

664033, г. Иркутск, ул. Лермонтова, 337; 664049, г. Иркутск, Юбилейный, 100; 664003, г. Иркутск, ул. Красного Восстания, 1

Dr. Sc. (Med.), Professor, Deputy Director for Science; Professor at the Department of Ophthalmology; Professor at the Department of Eye Diseases

Lermontova str. 337, Irkutsk 664033; Yubileyniy 100, Irkutsk664049; Krasnogo Vosstaniya str. 1, Irkutsk 664003

tnyurieva@mail.ruИркутский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» имени академика С.Н. Фёдорова» Минздрава РоссииIrkutsk Branch of S.N. Fyodorov Eye Microsurgery Federal State InstitutionИркутский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» имени академика С.Н. Фёдорова» Минздрава России; Иркутская государственная медицинская академия последипломного образования – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава РоссииIrkutsk Branch of S.N. Fyodorov Eye Microsurgery Federal State Institution; Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuing Professional Education20222405202272147166Copyright © Жукова С.И., Юрьева Т.Н., 20222022Жукова С.И., Юрьева Т.Н.Zhukova S.I., Iureva T.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actabiomedica.ru/jour/article/view/3434

Оптическая когерентная томография (ОКТ) в повседневной рутинной практике является методом выбора инструментальной диагностики глаукомы у взрослых. Являясь неинвазивным и безопасным методом визуализации структурных изменений сетчатки и зрительного нерва, метод представляет особую ценность в педиатрической практике. Вместе с тем ОКТ-диагностика у детей сопряжена с определёнными трудностями как при проведении исследования, так и при интерпретации результатов сканирования. В этом обзоре обобщены данные литературы и собственных исследований в диагностике и мониторинге врождённой и ювенильной глаукомы с позиций собственного многолетнего клинического опыта использования оптической когерентной томографии. Рассмотрены физиологические изменения сетчатки и зрительного нерва, акцентировано внимание на необходимости создания педиатрической нормативной базы данных толщины сетчатки, обозначены факторы, определяющие нормальный диапазон полученных данных и позволяющие отличить физиологические процессы от патологических. В качестве примеров представлены клинические случаи, подтверждающие ценность ОКТ при сочетанной патологии.

Optical coherence tomography (OCT) in everyday routine practice is the method of choice for the instrumental diagnosis of glaucoma in adults. As a non-invasive and safe method of visualizing structural changes in the retina and the optic nerve, the method is of particular value in pediatric practice. At the same time, OCT diagnostics in children is associated with certain difficulties, both during the study and when interpreting the scan results.

This review summarizes the data from the literature and our own research in the diagnosis and monitoring of congenital and juvenile glaucoma from the standpoint of our own long-term clinical experience in using optical coherence tomography. We consider the physiological changes of the retina and optic nerve, attention is focused on the need to create a pediatric regulatory database of retinal thickness, the factors that determine the normal range of the data obtained and allow distinguishing physiological processes from pathological ones are identified. Clinical cases confirming the value of OCT in combined pathology are presented as examples.

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The authors declare that there are no conflicts of interest present.