<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2021-6.6-1.25</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-3129</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOLOGY</subject></subj-group></article-categories><title-group><article-title>Толщина хориоидеи, цилиарного тела и сетчатки глаза по данным оптической когерентной томографии у пациентов после Фемто-ЛАЗИК</article-title><trans-title-group xml:lang="en"><trans-title>Thickness of the choroid, ciliary body and retina according to optical coherence tomography in patients after Femto LASIK</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2100-2972</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сахнов</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sakhnov</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, кандидат экономических наук, академик РАЕН, директор</p><p>350012, г. Краснодар, ул. Красных партизан, 6, Россия</p></bio><bio xml:lang="en"><p> Cand. Sc. (Med.), Cand. Sc. (Econ.), Academician of the Russian Academy of Natural Sciences, Director</p><p>Krasnykh partisan str. 6, Krasnodar 350012, Russian Federation </p></bio><email xlink:type="simple">office@okocentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4394-7723</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клокова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Klokova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, заведующая отделением рефракционной хирургии</p><p>350012, г. Краснодар, ул. Красных партизан, 6, Россия</p></bio><bio xml:lang="en"><p> Cand. Sc. (Med.), Head of the Department of Refractive Surger </p><p>Krasnykh partisan str. 6, Krasnodar 350012, Russian Federation </p></bio><email xlink:type="simple">oaklokova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бронская</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bronskaya</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p> врач-офтальмолог отделения рефракционной хирургии</p><p>350012, г. Краснодар, ул. Красных партизан, 6, Россия</p></bio><bio xml:lang="en"><p> Ophthalmologist at the Department of Refractive Surgery </p><p>Krasnykh partisan str. 6, Krasnodar 350012, Russian Federation </p></bio><email xlink:type="simple">bronskaya_kf@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4555-6622</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гейденрих</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Geidenrikh</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p> врач-офтальмолог </p><p>350012, г. Краснодар, ул. Красных партизан, 6, Россия</p></bio><bio xml:lang="en"><p> Ophthalmologist </p><p>Krasnykh partisan str. 6, Krasnodar 350012, Russian Federation </p></bio><email xlink:type="simple">geydenrikh@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9239-1739</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дамашаускас</surname><given-names>Р. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Damashauskas</surname><given-names>R. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p> врач-офтальмолог </p><p>350012, г. Краснодар, ул. Красных партизан, 6, Россия</p></bio><bio xml:lang="en"><p> Ophthalmologist </p><p> Krasnykh partisan str. 6, Krasnodar 350012, Russian Federation </p></bio><email xlink:type="simple">quas87@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Краснодарский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» имени академика С.Н. Фёдорова» Минздрава России</institution></aff><aff xml:lang="en"><institution>Krasnodar Branch of the S. Fyodorov Eye Microsurgery Federal State Institution </institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2021</year></pub-date><volume>6</volume><issue>6-1</issue><fpage>221</fpage><lpage>228</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сахнов С.Н., Клокова О.А., Бронская А.Н., Гейденрих М.С., Дамашаускас Р.О., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Сахнов С.Н., Клокова О.А., Бронская А.Н., Гейденрих М.С., Дамашаускас Р.О.</copyright-holder><copyright-holder xml:lang="en">Sakhnov S.N., Klokova O.A., Bronskaya A.N., Geidenrikh M.S., Damashauskas R.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/3129">https://www.actabiomedica.ru/jour/article/view/3129</self-uri><abstract><p>Обоснование. В доступной литературе теме возможного влияния лазерной коррекции методом Фемто-ЛАЗИК на сосудистую оболочку миопического глаза посвящены единичные публикации. В связи с этим, на наш взгляд, сохраняется актуальность продолжения исследований в этом направлении.Цель настоящего исследования: изучить объём сетчатки в макулярной зоне, толщину хориоидеи и цилиарного тела с использованием оптической когерентной томографии на миопических глазах после лазерного кератомилеза in situ с фемтосопровождением в краткосрочном периоде.Материал и методы. 30 пациентов (30 правых глаз) возрасте от 20 до 35 лет, страдающих миопией слабой и средней степени, но без патологических изменений сетчатки по данным ОКТ, составили группу исследования. Всем пациентам была выполнена коррекция миопии методом Фемто-ЛАЗИК. До операции, через 4 часа и на следующий день им проводилось исследование объёма сетчатки в макулярной зоне, толщины хориоидеи и цилиарного тела с использованием ОКТ.Результаты. Анализ полученных результатов исследуемых параметров показал, что толщина цилиарного тела и объём сетчатки в макулярной зоне не претерпели статистически значимых изменений и оставались в пределах дооперационных значений (р &gt; 0,05). Нами была отмечена тенденция к увеличению толщины хориоидеи через 4 часа после операции, но проведённый статистический анализ не подтвердил статистическую значимость её изменений (р &gt; 0,05). На следующий день показатели толщины хориоидеи практически восстановились до дооперационного уровня (р &gt; 0,05).Заключение. Выполненное исследование объёма сетчатки в макулярной зоне, толщины хориоидеи и цилиарного тела с использованием ОКТ на миопических глазах в краткосрочном периоде после Фемто-ЛАЗИК показало отсутствие статистически значимых изменений изучаемых параметров, что косвенно свидетельствует о безопасности данного метода лазерной коррекции для заднего отрезка глаза.</p></abstract><trans-abstract xml:lang="en"><p>Background. In the available literature, there are isolated publications devoted to the topic of the possible effect of laser correction by the Femto LASIK method on the myopic eye choroid. In this connection, in our opinion, the relevance of continuing research in this direction remains.The aim of this study was to examine the volume of the retina in the macular zone, the thickness of the choroid and the ciliary body using optical coherence tomography on myopic eyes after femtosecond-assisted laser in situ keratomileusis in the short term.Material and methods. 30 patients (30 right eyes) aged 20 to 35 years, suffering from mild and moderate myopia, but without pathological changes in the retina according to OCT, made up the study group. All patients underwent myopia correction using the Femto LASIK method. Before the operation, after 4 hours and the next day, they underwent the examination of the retinal volume in the macular zone, the choroidal and the ciliary body thickness using OCTResults. The analysis of the obtained results of the studied parameters showed that the ciliary body thickness and the retinal volume in the macular zone did not undergo statistically signifi cant changes and remained within the preoperative values (p &gt; 0.05). We observed a tendency to an increase in the thickness of the choroid 4 hours after the operation, but the carried out statistical analysis did not confi rm the reliability of its changes (p &gt; 0.05). On the next day, the choroidal thickness indices practically recovered to the preoperative level (p &gt; 0.05).Conclusion. A study of the retinal volume in the macular zone, the thickness of the choroid and ciliary body using OCT in myopic eyes in the short term after Femto LASIK showed the absence of statistically signifi cant changes in the studied parameters, which indirectly indicates the safety of this method of laser correction for the posterior segment of the eye.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>миопия</kwd><kwd>Фемто-ЛАЗИК</kwd><kwd>хориоидея</kwd><kwd>цилиарное тело</kwd><kwd>макулярная зона сетчатки</kwd><kwd>оптическая когерентная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myopia</kwd><kwd>Femto LASIK</kwd><kwd>choroid</kwd><kwd>ciliary body</kwd><kwd>macular area of the retina</kwd><kwd>optical coherence tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Callou TP, Garcia R, Mukai A, Giacomin NT, Guimarães de Souza R, Bechara SJ. Advances in femtosecond laser technology. Clin Ophthalmoly. 2016; 10: 697-703. doi: 10.2147/OPTH.S99741</mixed-citation><mixed-citation xml:lang="en">Callou TP, Garcia R, Mukai A, Giacomin NT, Guimarães de Souza R, Bechara SJ. Advances in femtosecond laser technology. Clin Ophthalmoly. 2016; 10: 697-703. doi: 10.2147/OPTH.S99741</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Slade SG. The use of the femtosecond laser in the customization of corneal flaps in laser in situ keratomileusis. Curr Opin Ophthalmol. 2007; 18(4): 314-317. doi: 10.1097/ICU.0b013e3281bd88a0</mixed-citation><mixed-citation xml:lang="en">Slade SG. The use of the femtosecond laser in the customization of corneal flaps in laser in situ keratomileusis. Curr Opin Ophthalmol. 2007; 18(4): 314-317. doi: 10.1097/ICU.0b013e3281bd88a0</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kymionis GD, Kankariya VP, Plaka AD, Reinstein DZ. Femtosecond laser technology in corneal refractive surgery: A review. J Refract Surg. 2012; 28(12): 912-920. doi: 10.3928/1081597x-20121116-01</mixed-citation><mixed-citation xml:lang="en">Kymionis GD, Kankariya VP, Plaka AD, Reinstein DZ. Femtosecond laser technology in corneal refractive surgery: A review. J Refract Surg. 2012; 28(12): 912-920. doi: 10.3928/1081597x-20121116-01</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Gao S, Li S, Liu L, Wang Y, Ding H, Li L, et al. Early changes in ocular surface and tear inflammatory mediators after smallincision lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis. PloS One. 2014; 9(9): e107370. doi: 10.1371/journal.pone.0107370</mixed-citation><mixed-citation xml:lang="en">Gao S, Li S, Liu L, Wang Y, Ding H, Li L, et al. Early changes in ocular surface and tear inflammatory mediators after smallincision lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis. PloS One. 2014; 9(9): e107370. doi: 10.1371/journal.pone.0107370</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">de Medeiros FW, Kaur H, Agrawal V, Chaurasia SS, Hammel J, Dupps WJ Jr, et al. Effect of femtosecond laser energy level on corneal stromal cell death and inflammation. J Refract Surg. 2009; 25(10): 869-874. doi: 10.3928/1081597X-20090917-08</mixed-citation><mixed-citation xml:lang="en">de Medeiros FW, Kaur H, Agrawal V, Chaurasia SS, Hammel J, Dupps WJ Jr, et al. Effect of femtosecond laser energy level on corneal stromal cell death and inflammation. J Refract Surg. 2009; 25(10): 869-874. doi: 10.3928/1081597X-20090917-08</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Астахов Ю.С., Белехова С.Г. Толщина хориоидеи при миопии различной степени. Офтальмологические ведомости. 2013; 6(4): 34-38.</mixed-citation><mixed-citation xml:lang="en">Astakhov YuS, Belekhova SG. Choroidal thickness in eyes with different degrees of myopia. Ophthalmology Journal. 2013; 6(4): 34-38. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Wong CW, Phua V, Lee SY, Wong TY, Cheung CM. Is choroidal or scleral thickness related to myopic macular degeneration? Invest Ophthalmol Vis Sci. 2017; 58(2): 907-913. doi: 10.1167/Iovs.16-20742</mixed-citation><mixed-citation xml:lang="en">Wong CW, Phua V, Lee SY, Wong TY, Cheung CM. Is choroidal or scleral thickness related to myopic macular degeneration? Invest Ophthalmol Vis Sci. 2017; 58(2): 907-913. doi: 10.1167/Iovs.16-20742</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Summers JA. The choroid as a sclera growth regulator. Exp Eye Res. 2013; 114: 120-127. doi: 10.1016/J.EXER.2013.03.008</mixed-citation><mixed-citation xml:lang="en">Summers JA. The choroid as a sclera growth regulator. Exp Eye Res. 2013; 114: 120-127. doi: 10.1016/J.EXER.2013.03.008</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Li M, Cheng H, Yuan Y, Wang J, Chen Q, Me R, et al. Change in choroidal thickness and the relationship with accommodation following myopic excimer laser surgery. Eye (Lond). 2016; 30(7): 972-978. doi: 10.1038/EYE.2016.75</mixed-citation><mixed-citation xml:lang="en">Li M, Cheng H, Yuan Y, Wang J, Chen Q, Me R, et al. Change in choroidal thickness and the relationship with accommodation following myopic excimer laser surgery. Eye (Lond). 2016; 30(7): 972-978. doi: 10.1038/EYE.2016.75</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Xu Z, Gui S, Huang J, Li Y, Lu F, Hu L. Effect of femtosecond laser in situ keratomileusis on the choriocapillaris perfusion and choroidal thickness in myopic patients. Curr Eye Res. 2021; 46(6): 878-884. doi: 10.1080/02713683.2020.1833350</mixed-citation><mixed-citation xml:lang="en">Xu Z, Gui S, Huang J, Li Y, Lu F, Hu L. Effect of femtosecond laser in situ keratomileusis on the choriocapillaris perfusion and choroidal thickness in myopic patients. Curr Eye Res. 2021; 46(6): 878-884. doi: 10.1080/02713683.2020.1833350</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Fontaine M, Gaucher D, Sauer A, Speeg-Schatz C. Choroidal thickness and ametropia in children: A longitudinal study. Eur J Ophthalmol. 2017; 27(6): 730-734. doi: 10.5301/ejo.5000965</mixed-citation><mixed-citation xml:lang="en">Fontaine M, Gaucher D, Sauer A, Speeg-Schatz C. Choroidal thickness and ametropia in children: A longitudinal study. Eur J Ophthalmol. 2017; 27(6): 730-734. doi: 10.5301/ejo.5000965</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ahn SJ, Park KH, Woo SJ. Subfoveal choroidal thickness changes following anti-vascular endothelial growth factor therapy in myopic choroidal neovascularization. Invest Ophthalmol Vis Sci. 2015; 56(10): 5794-800. doi: 10.1167/iovs.14-16006</mixed-citation><mixed-citation xml:lang="en">Ahn SJ, Park KH, Woo SJ. Subfoveal choroidal thickness changes following anti-vascular endothelial growth factor therapy in myopic choroidal neovascularization. Invest Ophthalmol Vis Sci. 2015; 56(10): 5794-800. doi: 10.1167/iovs.14-16006</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Flores-Moreno I, Lugo F, Duker F, Duker JS, Ruiz-Moreno JM. The relationship between axial length and choroidal thickness in eyes with high myopia. Am J Ophthalmol. 2013; 155(2): 314-319. doi: 10.1016/J.AJO.2012.07.015</mixed-citation><mixed-citation xml:lang="en">Flores-Moreno I, Lugo F, Duker F, Duker JS, Ruiz-Moreno JM. The relationship between axial length and choroidal thickness in eyes with high myopia. Am J Ophthalmol. 2013; 155(2): 314-319. doi: 10.1016/J.AJO.2012.07.015</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Тарутта Е.П., Маркосян Г.А., Сианосян А.А., Милаш С.В. Толщина хориоидеи при различных видах рефракции и ее динамика после склероукрепляющих операций. Российский офтальмологический журнал. 2017; 10(4): 48-53. doi: 10.21516/2072-0076-2017-10-4-48-53</mixed-citation><mixed-citation xml:lang="en">Tarutta EP, Markosyan GA, Sianosyan AA, Milash SV. Choroidal thickness in varied types of refraction and its changes after sclera strengthening surgeries. Russian Ophthalmological Journal. 2017; 10(4): 48-53. (In Russ.). doi: 10.21516/2072-0076-2017-10-4-48-53</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Tomita M, Watabe M, Yukawa S, Nakamura N, Nakamura T, Magnago T. Safety, efficacy, and predictability of laser in situ keratomileusis to correct myopia or myopic astigmatism with a 750Hz scanning-spot laser system. J Cataract Refract Surg. 2014; 40(2): 251-258. doi: 10.1016/j.jcrs.2013.07.043</mixed-citation><mixed-citation xml:lang="en">Tomita M, Watabe M, Yukawa S, Nakamura N, Nakamura T, Magnago T. Safety, efficacy, and predictability of laser in situ keratomileusis to correct myopia or myopic astigmatism with a 750Hz scanning-spot laser system. J Cataract Refract Surg. 2014; 40(2): 251-258. doi: 10.1016/j.jcrs.2013.07.043</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Mirshahi A, Scharioth GB, de Ortueta D, Baatz H. Posterior segment complications of laser in situ keratomileusis (LASIK)-a survey of the literature. Klin Monbl Augenheilkd. 2006; 223: 721-725. doi: 10.1055/s-2006-926709</mixed-citation><mixed-citation xml:lang="en">Mirshahi A, Scharioth GB, de Ortueta D, Baatz H. Posterior segment complications of laser in situ keratomileusis (LASIK)-a survey of the literature. Klin Monbl Augenheilkd. 2006; 223: 721-725. doi: 10.1055/s-2006-926709</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Torabi H, Daryabari SH. Choroidal neovascularization following photorefractive keratectomy. J Curr Ophthalmol. 2017; 29(1): 63-65. doi: 10.1016/j.joco.2016.08.009</mixed-citation><mixed-citation xml:lang="en">Torabi H, Daryabari SH. Choroidal neovascularization following photorefractive keratectomy. J Curr Ophthalmol. 2017; 29(1): 63-65. doi: 10.1016/j.joco.2016.08.009</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
