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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2021-6.6-1.11</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-3115</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOLOGY</subject></subj-group></article-categories><title-group><article-title>О сроках проведения витреальной хирургии при активной ретинопатии недоношенных.</article-title><trans-title-group xml:lang="en"><trans-title>Time of vitreal surgery for active retinopathy of prematurity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0840-2675</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терещенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshchenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, директор</p><p>248007, г. Калуга, ул. Святослава Фёдорова, 5, Россия</p></bio><bio xml:lang="en"><p> Dr. Sc. (Med.), Director</p><p>Svyatoslava Fedorova str. 5, Kaluga 248007, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9202-5181</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трифаненкова</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Trifanenkova</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, заместитель директора по научной работе </p><p>248007, г. Калуга, ул. Святослава Фёдорова, 5, Россия</p></bio><bio xml:lang="en"><p> Dr. Sc. (Med.), Deputy Director for Research </p><p>Svyatoslava Fedorova str. 5, Kaluga 248007, Russian Federation</p></bio><email xlink:type="simple">nauka@eye-kaluga.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2135-8162</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юдина</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yudina</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, заведующая отделением витреоретинальной хирургии</p><p>248007, г. Калуга, ул. Святослава Фёдорова, 5, Россия</p></bio><bio xml:lang="en"><p> Cand. Sc. (Med.), Head of the Department of Vitreoretinal Surgery </p><p>Svyatoslava Fedorova str. 5, Kaluga 248007, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1385-0330</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терещенкова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshchenkova</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, заведующая детским хирургическим отделением</p><p>248007, г. Калуга, ул. Святослава Фёдорова, 5, Россия</p></bio><bio xml:lang="en"><p> Cand. Sc. (Med.), Head of the Pediatric Surgical Department </p><p>Svyatoslava Fedorova str. 5, Kaluga 248007, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7320-9209</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ерохина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Erokhina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> заведующая диагностическим отделением № 2</p><p>248007, г. Калуга, ул. Святослава Фёдорова, 5, Россия</p></bio><bio xml:lang="en"><p> Head of the Diagnostic Department No. 2 </p><p>Svyatoslava Fedorova str. 5, Kaluga 248007, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8396-4013</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сидорова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sidorova</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, заведующая отделением лазерной хирургии донной патологии глаза</p><p>248007, г. Калуга, ул. Святослава Фёдорова, 5, Россия</p></bio><bio xml:lang="en"><p> Cand. Sc. (Med.), Head of the Department of Laser Surgery of Bottom Eye Pathology </p><p>Svyatoslava Fedorova str. 5, Kaluga 248007, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Калужский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» имени академика С.Н. Фёдорова» Минздрава России</institution></aff><aff xml:lang="en"><institution>Kaluga Branch of S. Fyodorov Eye Microsurgery Federal State Institution </institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2021</year></pub-date><volume>6</volume><issue>6-1</issue><fpage>96</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Терещенко А.В., Трифаненкова И.Г., Юдина Н.Н., Терещенкова М.С., Ерохина Е.В., Сидорова Ю.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Терещенко А.В., Трифаненкова И.Г., Юдина Н.Н., Терещенкова М.С., Ерохина Е.В., Сидорова Ю.А.</copyright-holder><copyright-holder xml:lang="en">Tereshchenko A.V., Trifanenkova I.G., Yudina N.N., Tereshchenkova M.S., Erokhina E.V., Sidorova Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/3115">https://www.actabiomedica.ru/jour/article/view/3115</self-uri><abstract><p>Обоснование. Анатомические и функциональные результаты хирургии ретинопатии недоношенных (РН) определяются не только стадией патологического процесса, но и зависят от сроков её проведения.Цель исследования: оценить эффективность витрэктомии при тяжёлой активной ретинопатии недоношенных в зависимости от сроков проведения хирургического лечения.Методы. Витреоретинальная хирургия проведена 138 детям (198 глаз) с тяжёлыми стадиями активной РН. Все пациенты были поделены на три группы в зависимости от сроков хирургического лечения: 1-я группа – 42–48 недель постконцептуального возраста (ПКВ), при прогрессировании РН после лазеркоагуляции сетчатки (ЛКС), 2-я – 39–41-я неделя ПКВ, при прогрессировании РН после ЛКС, 3-я – 36–39 недель ПКВ, без ранее проведённой ЛКС. Всем пациентам была выполнена 3-портовая транссклеральная 27-G витрэктомия. В послеоперационном периоде результаты витрэктомии оценивались по анатомическому прилеганию сетчатки. Срок наблюдения составил 12 месяцев.Результаты . В 1-й группе в 31 случае (73,8 %) хирургическое вмешательство завершили силиконовой тампонадой. К концу срока наблюдения анатомическое прилежание сетчатки было достигнуто в 17 глазах (40,5 %). Во 2-й группе хирургическое лечение было завершено силиконовой тампонадой в 29 глазах (42 %). К концу срока наблюдения анатомическое прилегание сетчатки достигнуто в 52 глазах (75 %). В 3-й группе хирургическое вмешательство завершили силиконовой тампонадой в 11 из 87 глаз (12,6 %). Анатомическое прилегание сетчатки было достигнуто в 80 глазах (92 %).Заключение. Несвоевременная витрэктомия (42–48 недель ПКВ) в случаях прогрессирования РН после ЛКС привела к худшему результату. При прогрессировании РН после лазерного лечения следует проводить раннюю витрэктомию (39–41-я неделя ПКВ). Первичную витрэктомию необходимо проводить, когда упущены оптимальные сроки лазерного лечения (после 36-й недели ПКВ).</p></abstract><trans-abstract xml:lang="en"><p>Background. The anatomical and functional results of surgery for retinopathy of prematurity (ROP) are determined not only by the stage of the pathological process, but also depend on the timing of its implementation.The aim: to estimate the effectiveness of vitrectomy for severe active retinopathy of prematurity, depending on the timing of surgical treatment.Methods. Vitreoretinal surgery was performed in 138 children (198 eyes) with severe stages of ROP. All patients were divided into three groups depending on the timing of surgical treatment: group 1 – 42–48 weeks of postconceptual age (PCA), with the progression of ROP after laser coagulation of the retina (LCS), group 2 – 39–41 weeks of PCA, with the progression of ROP after LCS, group 3 – 36–39 weeks of PCA, without previous LCS. A 3-port transscleral 27-G vitrectomy was performed by all patients. At the postoperative period, the results of vitrectomy were estimated by the anatomical attachment of the retina. The follow-up period was 12 months. Results. In group 1, in 31 cases (73.8 %), the surgical intervention was completed with silicone tamponade. By the end of the follow-up period, anatomical retinal attachment was achieved in 17 eyes (40.5 %).In group 2, surgical intervention was completed with silicone tamponade in 29 eyes (42 %). By the end of the follow-up period, anatomical retinal attachment was achieved in 52 eyes (75 %).In group 3, surgical intervention was completed with silicone tamponade in 11 of 87 eyes (12.6 %). Anatomical retinal attachment was achieved in 80 eyes (92 %).Conclusion. Untimely vitrectomy (42–48 weeks of PCA) in cases of ROP progression after LCR led to a worse result. If progress of ROP after laser treatment happens, early vitrectomy (39–41 weeks of PCA) should be performed. Primary vitrectomy should be performed in case of the optimal timing of laser treatment has been missed (after 36 weeks of PCV).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>витрэктомия</kwd><kwd>активная ретинопатия недоношенных</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vitrectomy</kwd><kwd>active retinopathy of prematurity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Vartan ian RJ, Besirli CG, Barks JD, Andrews CA, Musch DC. Trends in the screening and treatment of retinopathy of prematurity. Pediatrics. 2017; 139(1): e20161978. doi: 10.1542/peds.2016-1978</mixed-citation><mixed-citation xml:lang="en">Vartan ian RJ, Besirli CG, Barks JD, Andrews CA, Musch DC. Trends in the screening and treatment of retinopathy of prematurity. 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