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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2021-6.1.14</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-2625</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОФЕССИОНАЛЬНЫЕ ЗАБОЛЕВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL DISEASES</subject></subj-group></article-categories><title-group><article-title>Взаимосвязь между нейропсихологическими показателями и уровнем постоянного потенциала у пациентов с профессиональными заболеваниями от воздействия физических факторов</article-title><trans-title-group xml:lang="en"><trans-title>The Relationship between Neuropsychological Performance and Level of Direct Current Potential in Patients with Occupational Diseases from Exposure to Physical Factors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4842-6791</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевченко</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchenko</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шевченко Оксана Ивановна – кандидат биологических наук, старший научный сотрудник лаборатории профессиональной и экологически обусловленной патологии</p><p>665827, г. Ангарск, 12А микрорайон, 3</p></bio><bio xml:lang="en"><p>Oksana I. Shevchenko – Cand. Sc. (Biol.), Senior Research Officer at the Laboratory of the Professional and Ecologically Caused Pathology</p><p>12А Microdistrict 3, Angarsk 665827</p></bio><email xlink:type="simple">oich68@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0013-8013</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лахман</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lakhman</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лахман Олег Леонидович – доктор медицинских наук, профессор, профессор РАН, директор</p><p>665827, г. Ангарск, 12А микрорайон, 3</p></bio><bio xml:lang="en"><p>Oleg L. Lakhman – Dr. Sc. (Med.), Professor, Professor of Russian Academy of Sciences, Director</p><p>12А Microdistrict 3, Angarsk 665827</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>East-Siberian Institute of Medical and Ecological Research</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Восточно-Сибирский институт медико-экологических исследований»</institution></aff><aff xml:lang="en"><institution>East-Siberian Institute of Medical and Ecological Research</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2021</year></pub-date><volume>6</volume><issue>1</issue><fpage>94</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шевченко О.И., Лахман О.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Шевченко О.И., Лахман О.Л.</copyright-holder><copyright-holder xml:lang="en">Shevchenko O.I., Lakhman O.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/2625">https://www.actabiomedica.ru/jour/article/view/2625</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: выявить особенности нарушений нейропсихологических показателей в зависимости от изменения уровня постоянного потенциала у пациентов с профессиональными заболеваниями от воздействия  физических  факторов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Обследовано 60 пациентов с вибрационной болезнью, обусловленной воздействием локальной вибрации (I группа), 106 пациентов с вибрационной болезнью, обусловленной сочетанным воздействием локальной и общей вибрации (II группа), 101 пилот гражданской авиации с установленным диагнозом профессиональной нейросенсорной тугоухости (III группа), и 50 здоровых мужчин (IV, группа сравнения), которые по специфике профессиональной деятельности не подвергались воздействию вибрации и шума. Применяли методы нейроэнергокартирования, нейропсихологического тестирования.</p></sec><sec><title>Результаты</title><p>Результаты. В I–II группах по сравнению с IV группой выявлено увеличение локальных уровней постоянного потенциала в центральном, правом височном, центральном лобном отделах головного мозга (2,3 (6,5–3,8); –0,3 (–2,1–2,1); 2,1 (–3,4–6,8) и –0,3 (–3,1–4,3); –2,24 (–6,4–3,8); 0,9 (–3,1–8,5) мВ при р = 0,005, 0,007 и 0,004 соответственно). Различия значений градиентов уровней постоянного потенциала у лиц III группы при сопоставлении с IV группой достигали уровня значимости в центральном, височных, затылочном отведениях относительно центрального лобного (–5,0 (–13,1–3,8); –4,1 (–9,4–5,1); –2,1 (–10,9–6,6); –6,3 (–15,3–1,8) и 2,9 (–3,0–10,6); 2,2 (–4,5–13,8); 5,6 (–7,6–14,1); –1,4 (–7,5–3,9) мВ при р = 0,008; 0,009; 0,009 и 0,007 соответственно). Когнитивные нарушения у пациентов I–III групп при сопоставлении с IV группой соответствуют легко выраженному расстройству динамического, конструктивного праксиса и экспрессивной речи (1,40 (0–1,6); 1,43 (0–1,7); 1,2 (0–1,5) и 0,3 (0–1); 0,2 (0–1); 0,06 (0–1), баллов при р = 0,008, 0,008 и 0,009 соответственно).</p></sec><sec><title>Заключение</title><p>Заключение. Общим нейрофункциональным признаком легко выраженного нарушения деятельности когнитивной сферы при профессиональных заболеваниях, обусловленных воздействием физических факторов, является повышение уровней постоянного потенциала в лобно-центральных и теменно-затылочных отделах преимущественно левого полушария головного мозга.</p></sec></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to identify the peculiarities of neuropsychological indices disorders depending on changes in the level of constant potential in patients with occupational diseases as a result of physical factors.</p><sec><title>Materials and methods</title><p>Materials and methods. The study involved 60 patients with vibration disease caused by local vibration (group I), 106 patients with vibration disease caused by combined exposure to local and general vibration (group II), 101 civil aviation pilots with an established diagnosis of professional sensorineural hearing loss (group III), and 50 healthy men (group IV, comparison group) who were not exposed to vibration and noise due to the specifics of their professional activities. Methods of neuro-energy mapping and neuropsychological testing were used.</p></sec><sec><title>Results</title><p>Results. In groups I–II, compared with group IV, an increase in local levels of constant potential (DC-potential level) in the central, right temporal, and central frontal parts of the brain (2.3 (6.5–3.8) mV; –0.3 (–2.1–2.1); 2.1 (–3.4–6.8) and –0.3 (–3.1–4.3); –2.24 (–6.4–3.8); 0.9 (–3.1–8.5) mV at p = 0.005, 0.007 and 0.004 respectively). Differences in the values of DC-potential level gradients in individuals of group III when compared with group IV reached the level of significance in the central, temporal, occipital leads relative to the central frontal (–5.0 (–13.1–3.8); –4.1 (–9.4–5.1); –2.1 (–10.9–6.6); –6.3 (–15.3–1.8) and 2.9 (–3.0–10.6); 2.2 (–4.5–13.8); 5.6 (–7.6–14.1); –1.4 (–7.5–3.9) mV at p = 0.008; 0.009; 0.009, and 0.007 respectively). Cognitive disorders in patients of groups I–III when compared with group IV correspond to a mild disorder of dynamic, constructive praxis and expressive speech (1.40 (0–1,6); 1.43 (0–1,7); 1.2 (0–1,5) and 0.3 (0–1); 0.2 (0–1); 0.06 (0–1) points at p = 0.008, 0.008 and 0.009 respectively).</p></sec><sec><title>Conclusions</title><p>Conclusions. A common neurofunctional sign of a mild impairment of the cognitive sphere in occupational diseases caused by physical factors is an increase in direct current potential level in the frontal-central and parieto-occipital regions, predominantly of the left hemisphere of the brain. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>вибрационная болезнь</kwd><kwd>профессиональная нейросенсорная тугоухость</kwd><kwd>энергетический обмен головного мозга</kwd><kwd>уровень постоянного потенциала</kwd><kwd>нейропсихологическое тестирование</kwd><kwd>когнитивные  нарушения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vibration disease and occupational sensorineural hearing loss</kwd><kwd>the energy metabolism of the brain</kwd><kwd>DC-potential level</kwd><kwd>neuropsychological testing</kwd><kwd>cognitive impairment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бирюкбаева Г.Н. 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