actabiomedicaActa Biomedica ScientificaActa Biomedica Scientifica2541-94202587-9596Scientific Centre for Family Health and Human Reproduction Problems10.29413/ABS.2020-5.6.9actabiomedica-2499Research ArticleЛЕКЦИИLECTURESРоль лизосом в онкогенезе: акцент на деградацию внеклеточного матриксаThe Role of Lysosomes in the Cancer Progression: Focus on the Extracellular Matrix Degradationhttps://orcid.org/0000-0002-0270-404XТруханИ. С.TrukhanI. S.

кандидат биологических наук, старший научный сотрудник

664003, г. Иркутск, ул. Борцов Революции, 1, Россия

PREDEL4@yandex.ruhttps://orcid.org/0000-0002-2540-4525ДреминаН. Н.DreminaN. N.

кандидат биологических наук, старший научный сотрудник

664003, г. Иркутск, ул. Борцов Революции, 1, Россия

Bortsov Revolyutsii str. 1, Irkutsk 664003, Russian Federation

drema76@mail.ruhttps://orcid.org/0000-0003-3980-050XШурыгинаИ. А.ShuryginaI. A.

доктор медицинских наук, профессор РАН, заместитель директора по научной работе

664003, г. Иркутск, ул. Борцов Революции, 1, Россия

Bortsov Revolyutsii str. 1, Irkutsk 664003, Russian Federation

irinashurygina@gmail.comФГБНУ «Иркутский научный центр хирургии и травматологии»РоссияIrkutsk Scientific Centre of Surgery and TraumatologyRussian Federation202014012021567787Copyright &#x00A9; Трухан И.С., Дремина Н.Н., Шурыгина И.А., 20212021Трухан И.С., Дремина Н.Н., Шурыгина И.А.Trukhan I.S., Dremina N.N., Shurygina I.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actabiomedica.ru/jour/article/view/2499лизосомыинвадоподиивнеклеточный матрикскатепсиныметастазированиеlysosomesinvadopodiaextracellular matrixcathepsinsmetastasisReferencesBallabio A, Bonifacino JS. Lysosomes as dynamic regulators of cell and organismal homeostasis. Nat Rev Mol Cell Biol. 2020; 21: 101-118. doi: 10.1038/s41580-019-0185-4Ballabio A, Bonifacino JS. Lysosomes as dynamic regulators of cell and organismal homeostasis. 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The authors declare that there are no conflicts of interest present.