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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2020-5.4.14</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-2399</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGERY</subject></subj-group></article-categories><title-group><article-title>Роль неустойчивого гемостаза в развитии специфических послеоперационных осложнений (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Unstable Hemostasis and Specific Postoperative Complications (Literature Review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7388-1679</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедева Дарья Владимировна – аспирант кафедры госпитальной хирургии </p><p>664003, г. Иркутск, ул. Красного Восстания, 1</p></bio><bio xml:lang="en"><p>Darya V. Lebedeva – Postgraduate at the Department of Advanced Level Surgery </p><p>Krasnogo Vosstaniya str. 1, Irkutsk 664003</p></bio><email xlink:type="simple">daria_lebe@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2081-8665</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильичева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilyicheva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ильичева Елена Алексеевна – доктор медицинских наук, профессор, заведующая научным отделом клинической хирургии; врач-хирург хирургического торакального отделения </p><p>664003, г. Иркутск, ул. Борцов Революции, 1</p><p>664049, г. Иркутск, Юбилейный, 100 </p></bio><bio xml:lang="en"><p>Elena A. Ilyicheva – Dr. Sc. (Med.), Professor, Head of the Scientific Department of Clinical Surgery; Surgeon at the Thoracic Surgery Unit </p><p>Bortsov Revolyutsii str. 1, Irkutsk 664003</p><p>Yubileyniy 100, Irkutsk 664049 </p></bio><email xlink:type="simple">lena_isi@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Иркутский научный центр хирургии и травматологии»; ГБУЗ «Иркутская ордена «Знак почёта» областная клиническая больница»</institution></aff><aff xml:lang="en"><institution>Irkutsk Scientific Centre of Surgery and Traumatology;  Irkutsk Regional Clinical Hospital</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>08</day><month>09</month><year>2020</year></pub-date><volume>5</volume><issue>4</issue><fpage>98</fpage><lpage>102</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лебедева Д.В., Ильичева Е.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Лебедева Д.В., Ильичева Е.А.</copyright-holder><copyright-holder xml:lang="en">Lebedeva D.V., Ilyicheva E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/2399">https://www.actabiomedica.ru/jour/article/view/2399</self-uri><abstract><p>Периоперационные кровотечения занимают ведущее место в структуре осложнений хирургических вмешательств и, несмотря на стремительное развитие хирургии, остаются актуальными до сих пор. Помимо роста летальности, кровотечения могут становиться причиной развития других послеоперационных осложнений, приводящих к инвалидизации пациентов и снижению качества жизни во всех возрастных группах. Большинство периоперационных кровотечений обусловлены техническими ошибками. В данном обзоре литературе освещается проблема периоперационных кровотечений с точки зрения нарушения коагуляционных возможностей организма. Рассмотрены основные этиопатогенетические особенности гемостаза при развитии данного осложнения. Приведён анализ послеперационных осложнений, причинами которых прямо или косвенно явились кровотечения во время или после операции. Продемонстрирована распространённость этих осложнений в различных областях хирургии. Акцентировано внимание на том, что более подробное изучение системы гемостаза, выявление предикторов трудностей гемостаза ещё до проведения хирургического вмешательства приведут к улучшению результатов хирургического лечения, снизят количество послеоперационных осложнений и длительность пребывания пациентов в стационаре. Соответственно, это приведёт к снижению стоимости лечения и увеличению удовлетворённости пациентов получаемой медицинской помощью. В связи с вышеперечисленным у хирургов и анестезиологов присутствует большая заинтересованность в предотвращении развития периоперационных кровотечений.</p></abstract><trans-abstract xml:lang="en"><p>Perioperative bleeding occupies a leading place among all surgical complications and, despite the rapid development of surgery, remains relevant to this day. In addition to an increase in mortality, bleeding can cause the development of other postoperative complications, which lead to disability of patients and to a decrease in the quality of life in all age groups. Most perioperative bleeding are caused by technical errors. This article reviews the problem of perioperative bleeding from the point of view of impaired coagulation capabilities of the body. The main etiopathogenetic features of hemostasis during the development of this complication are considered. The analysis of postoperative complications, which were directly or indirectly caused by bleeding during or after surgery, is presented. The prevalence of these complications in various areas of surgery has been demonstrated. More detailed study of the hemostasis system and the identification of predictors of hemostasis difficulties before the surgery may cause an improvement in the results of surgical treatment and reduce the number of postoperative complications and the duration of hospital stay. Accordingly, this will lead to a decrease in the cost of treatment and an increase in patient satisfaction with the medical care. In connection with the above, there is a great interest among surgeons and anesthesiologists in preventing the development of perioperative bleeding.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>интраопераоперационное кровотечение</kwd><kwd>послеоперационные осложнения</kwd><kwd>гемостаз</kwd><kwd>кровопотеря</kwd><kwd>операции на печени</kwd><kwd>нейрохирургия</kwd><kwd>тиреоидная хирургия</kwd><kwd>урология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>intraoperative bleeding</kwd><kwd>postoperative complications</kwd><kwd>hemostasis</kwd><kwd>blood loss</kwd><kwd>liver operations</kwd><kwd>neurosurgery</kwd><kwd>thyroid surgery</kwd><kwd>urology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Marietta M, Facchini L, Pedrazzi P, Busani S, Torelli G. Pathophysiology of bleeding in surgery. 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