<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-22</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Опыт хирургического лечения обструкции дуги аорты у детей в условиях антеградной селективной перфузии головного мозга</article-title><trans-title-group xml:lang="en"><trans-title>Our experience of surgical treatment of aortic arch obstruction in children in the presence of antegrade selective cerebral perfusion</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильинов</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Iljinov</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">ilinov_86@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якимова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimova</surname><given-names>Y. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивлев</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivlev</surname><given-names>A. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселев</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselev</surname><given-names>V. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гинько</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Ginko</surname><given-names>V. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривощеков</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivoshchekov</surname><given-names>Y. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шипулин</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shipulin</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плеханов</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Plekhanov</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт кардиологии»</institution></aff><aff xml:lang="en"><institution>Research Institute for Cardiology</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВПО «Бурятский государственный университет»; ФГБНУ «Иркутский научный центр хирургии и травматологии»; НУЗ «Отделенческая клиническая больница на ст. Улан-Удэ ОАО «РЖД»</institution></aff><aff xml:lang="en"><institution>Buryat State University; Irkutsk Scientific Center of Surgery and Traumatology; Regional Clinical Hospital at the station Ulan-Ude of OJSC “RZHD”</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2015</year></pub-date><volume>0</volume><issue>2</issue><fpage>15</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ильинов В.Н., Якимова Е.В., Ивлев А.Ю., Киселев В.О., Гинько В.Е., Кривощеков Е.В., Шипулин В.М., Плеханов А.Н., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Ильинов В.Н., Якимова Е.В., Ивлев А.Ю., Киселев В.О., Гинько В.Е., Кривощеков Е.В., Шипулин В.М., Плеханов А.Н.</copyright-holder><copyright-holder xml:lang="en">Iljinov V.N., Yakimova Y.V., Ivlev A.Y., Kiselev V.O., Ginko V.Y., Krivoshchekov Y.V., Shipulin V.M., Plekhanov A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/22">https://www.actabiomedica.ru/jour/article/view/22</self-uri><abstract><p>Целью данной работы стала оценка результатов лечения патологии дуги аорты в условиях селективной церебральной перфузии и умеренной гипотермии у детей. В исследование включены 97 пациентов с обструкцией дуги аорты. Всем пациентам выполнена реконструкция аорты. Общая летальность составила 4 %. Осложнения оперативного вмешательства выявлены в 7% случаев, в 4% случаев - со стороны органов дыхания, в 6% случаев - со стороны нервной системы. Мы считаем, что используемый нами метод является эффективным, безопасным и легко воспроизводимым способом устранения данной патологии.</p></abstract><trans-abstract xml:lang="en"><p>This work is about outcomes of surgical treatment aortic arch obstruction in children performed with the use of selective cerebral perfusion and moderate hypothermia. The study included 97 patients with aortic coarctation, recoarctation and hypoplastic aortic arch. The patients were divided into 3 groups. 75 patients with isolated coarctation and recoarctation or with concomitant atrial septal defects, patentforamen ovale and patent ductus arterious were assigned to the 1st group. The 2nd group included 13 patients with aortic arch obstruction and ventricular septal defects. The 3rd group consisted of 9 patients with coarctation, recoarctation and complex intracardiac anomalies. All patients underwent reconstruction of the aortic arch with selective cerebral perfusion and moderate hypothermia. Overall mortality rate was 4%. Postoperative complications took place in 7% of the cases: 1% - postoperative bleeding, 1% - paresis of the diaphragm, 2% - pneumothorax, 2% - chylothorax, and 1% of the cases - vocal cords paresis. Respiratory postoperative complications were registered in 5% of cases. In 6% of the cases patients had neurological postoperative complications. After the operation there was no gradientfound between the pressures on upper and lower extremities. We consider that antegrade selective cerebral perfusion and moderate hypothermia during aortic arch reconstruction are effective methods of brain and visceral organs protection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коарктация аорты</kwd><kwd>рекоарктация</kwd><kwd>гипоплазия дуги аорты</kwd><kwd>антеградная селективная церебральная перфузия</kwd><kwd>гипотермия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>aortic coarctation</kwd><kwd>recoarctation</kwd><kwd>aortic arch hypoplasia</kwd><kwd>antegrade selective cerebral perfusion</kwd><kwd>hypothermia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ильинов В.Н., Кривощеков Е.В., Шипулин В.М. Хирургическое лечение коарктации аорты в сочетании с гипоплазией дуги // Сибирский медицинский журнал. - 2014. - № 3, Т. 29. - С. 80-85. Iljinov V.N., Krivoshchekov E.V., Shipulin V.M. (2014). Surgical treatment of aorta coarctation in combination with aortic arch hypoplasia [Hirurgicheskoe lechenie koarktacii aorty v sochetanii s gipoplaziej dugi]. Sibirskij medicinskij zhurnal, 3 (29), 80-85.</mixed-citation><mixed-citation xml:lang="en">Ильинов В.Н., Кривощеков Е.В., Шипулин В.М. Хирургическое лечение коарктации аорты в сочетании с гипоплазией дуги // Сибирский медицинский журнал. - 2014. - № 3, Т. 29. - С. 80-85. Iljinov V.N., Krivoshchekov E.V., Shipulin V.M. (2014). Surgical treatment of aorta coarctation in combination with aortic arch hypoplasia [Hirurgicheskoe lechenie koarktacii aorty v sochetanii s gipoplaziej dugi]. Sibirskij medicinskij zhurnal, 3 (29), 80-85.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Синельников Ю.С., Корнилов И.А., Сойнов И.А. и др. Защита головного мозга при реконструкции дуги аорты у новорожденных // Патология кровообращения и кардиохирургия. - 2013. - № 3. - С. 4-7. Sinelnikov Y.S., Kornilov I.A., Soynov I.A. et al. (2013). Brain protection at the aortic arch reconstruction in newborns [Zashhita golovnogo mozga pri rekonstrukcii dugi aorty u novorozhdennyh]. Patologija krovoobrashhenija i kardiohirurgija (3), 4-7.</mixed-citation><mixed-citation xml:lang="en">Синельников Ю.С., Корнилов И.А., Сойнов И.А. и др. Защита головного мозга при реконструкции дуги аорты у новорожденных // Патология кровообращения и кардиохирургия. - 2013. - № 3. - С. 4-7. Sinelnikov Y.S., Kornilov I.A., Soynov I.A. et al. (2013). Brain protection at the aortic arch reconstruction in newborns [Zashhita golovnogo mozga pri rekonstrukcii dugi aorty u novorozhdennyh]. Patologija krovoobrashhenija i kardiohirurgija (3), 4-7.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Asou T., Kado H., Imoto Y. et al. (1996). Selective cerebral perfusion technique during aortic arch repair in neonates. Ann. Thorac. Surg., 5 (61), 1546-1548.</mixed-citation><mixed-citation xml:lang="en">Asou T., Kado H., Imoto Y. et al. (1996). Selective cerebral perfusion technique during aortic arch repair in neonates. Ann. Thorac. Surg., 5 (61), 1546-1548.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kouchoukos N. (2013). Kirklin/Barratt - Boyes cardiac surgery: morphology, diagnostic criteria, natural history, techniques, results, and indications, 67-132, 1718-1779.</mixed-citation><mixed-citation xml:lang="en">Kouchoukos N. (2013). Kirklin/Barratt - Boyes cardiac surgery: morphology, diagnostic criteria, natural history, techniques, results, and indications, 67-132, 1718-1779.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ly M., Roubertie F., Belli E. et al. (2011). Continuous perfusion for aortic arch repair: hypothermia versus normothermia. Ann. Thorac. Surg. (92), 942-948.</mixed-citation><mixed-citation xml:lang="en">Ly M., Roubertie F., Belli E. et al. (2011). Continuous perfusion for aortic arch repair: hypothermia versus normothermia. Ann. Thorac. Surg. (92), 942-948.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mavrodis C., Backer С. (2013). Pediatric cardiac surgery, 256-282.</mixed-citation><mixed-citation xml:lang="en">Mavrodis C., Backer С. (2013). Pediatric cardiac surgery, 256-282.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Mossad E., Machado S., Apostolakis J. (2007). Bleeding following deep hypothermia and circulatory arrest in children. Semin. Cardiothorac. Vasc. Anesth. (11), 34-46.</mixed-citation><mixed-citation xml:lang="en">Mossad E., Machado S., Apostolakis J. (2007). Bleeding following deep hypothermia and circulatory arrest in children. Semin. Cardiothorac. Vasc. Anesth. (11), 34-46.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ungerleider R., Pasquali S. et al. (2013). Contemporary patterns of surgery and outcomes for aortic coarctation: an analysis of the society of thoracic surgeons congenital heart surgery database. J. Thorac. Cardiovasc. Surg., 145 (1), 1-20.</mixed-citation><mixed-citation xml:lang="en">Ungerleider R., Pasquali S. et al. (2013). Contemporary patterns of surgery and outcomes for aortic coarctation: an analysis of the society of thoracic surgeons congenital heart surgery database. J. Thorac. Cardiovasc. Surg., 145 (1), 1-20.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
