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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.12737/21585</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-217</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Особенности интенсивной органосохраняющей терапии при выраженных послеродовых кровотечениях</article-title><trans-title-group xml:lang="en"><trans-title>Features of intensive organ-sparing therapy for massive postpartum hemorrhage</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крамарский</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kramarskiy</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">kramarskye@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ежова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ezhova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">irgpc@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сверкунова</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Sverkunova</surname><given-names>N. L.</given-names></name></name-alternatives><email xlink:type="simple">doctor-cha@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дудакова</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dudakova</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">vidun@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical Academy of Continuing Education</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ОГАУЗ «Иркутский городской перинатальный центр»</institution></aff><aff xml:lang="en"><institution>Perinatal Center of Irkutsk</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>28</day><month>05</month><year>2016</year></pub-date><volume>1</volume><issue>3(1)</issue><fpage>11</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крамарский В.А., Ежова И.В., Сверкунова Н.Л., Дудакова В.Н., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Крамарский В.А., Ежова И.В., Сверкунова Н.Л., Дудакова В.Н.</copyright-holder><copyright-holder xml:lang="en">Kramarskiy V.A., Ezhova I.V., Sverkunova N.L., Dudakova V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/217">https://www.actabiomedica.ru/jour/article/view/217</self-uri><abstract><p>Проанализированы истории родов с выраженными послеродовыми кровотечениями. Все женщины имели факторы риска послеродового кровотечения. Проводилась профилактика кровотечения транексамовой кислотой и эптакогом альфа. При кровотечении применялись сокращающие средства, инфузионная терапия, баллонная тампонада, щипцы по Бакшееву и хирургический гемостаз. В первые 2 часа после начала кровотечения переливалось от 150 до 160 % объема учтенной кровопотери. Своевременная поэтапная терапия с применением вышеуказанных технологий обеспечивает органосохраняющий эффект.</p></abstract><trans-abstract xml:lang="en"><p>Bleeding in pregnancy, childbirth and the postpartum period is one of the leading causes of maternal morbidity and mortality worldwide. There is no doubt that obstetric bleeding demands the development of improved methods for its diagnostics and treatment. We assessed the effectiveness of the treatment strategy for massive postpartum hemorrhage (PPH) with preservation of reproductive function, applied in the Perinatal Center of Irkutsk. We performed a retrospective analysis of 24 delivery cases, complicated by massive bleeding and successfully treated with preservation of reproductive organs. The massive nature of bleeding (&gt; 30 % of blood volume) was registered in 15 (62.5 %) cases, mild (&gt; 20 % but &lt;30 % of blood volume) - in 9 (37.5 %). Emergency operative delivery (cesarean section) was performed in 40 % of massive PPH cases and in 66.7 % of mild PPH cases. Uterotonic drugs were used in all PPH cases. When analyzing complex mechanical methods of PPH arrest, we noticed that in 20 % of cases balloon tamponade was used. In 33.3 % of mild PPH cases, balloon tamponade with great vessels ligation was performed. Thus, the most effective method was balloon tamponade coupled with Baksheev forceps and early surgical hemostasis. All in all, prevention of hemorrhage in risk groups and early fluid and surgical therapy, and also administration of uterotonic drugs in PPH treatment not only provide a hemostatic effect but also preserve reproductive function.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>профилактика</kwd><kwd>послеродовое кровотечение</kwd><kwd>инфузия</kwd><kwd>хирургический гемостаз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>prevention</kwd><kwd>postpartum hemorrhage</kwd><kwd>infusion</kwd><kwd>surgical hemostasis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ВОЗ. 10 ведущих причин смерти в мире. Информационный бюллетень. - 2014. - № 310. WHO (2014). The top 10 causes of death. Fact sheet [10 vedushchikh prichin smerti v mire. Informatsionnyy byulleten’], (310).</mixed-citation><mixed-citation xml:lang="en">ВОЗ. 10 ведущих причин смерти в мире. 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