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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29413/ABS.2019-4.4.19</article-id><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-2133</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОФТАЛЬМОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPHTHALMOLOGY</subject></subj-group></article-categories><title-group><article-title>Роль цветооппонентной периметрии и визоконтрастометрии в диагностике оптических невритов</article-title><trans-title-group xml:lang="en"><trans-title>Role of Color Perimetry and Visocontrastometry in Diagnosis of Optical Neuritis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5738-9059</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурлакова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Burlakova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурлакова Елена Валерьевна – врач-офтальмолог офтальмологического отделения</p><p>664003, г. Иркутск, ул. Красного Восстания, 1</p><p> </p></bio><bio xml:lang="en"><p>Elena V. Burlakova – Ophthalmologist at the Ophthalmology Department</p><p>1 Krasnogo Vosstania str., Irkutsk 664003</p></bio><email xlink:type="simple">okullina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1303-9030</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Швец</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shvets</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Швец Лидия Витальевна – врач-офтальмолог</p><p>664003, г. Иркутск, ул. Красного Восстания, 1</p></bio><bio xml:lang="en"><p>Lidiya V. Shvets – Ophthalmologist</p><p>1 Krasnogo Vosstania str., Irkutsk 664003</p></bio><email xlink:type="simple">lidiy.isa@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4264-4408</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щуко</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchuko</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щуко Андрей Геннадьевич – доктор медицинских наук, профессор, директор</p><p>664043, г. Иркутск, ул. Лермонтова, 337</p></bio><bio xml:lang="en"><p>Andrey G. Shchuko – Dr. Sc. (Med.), Director</p><p>337 Lermontov str., Irkutsk 664033</p></bio><email xlink:type="simple">if@mntk.irkutsk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Иркутский филиал ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>25</day><month>08</month><year>2019</year></pub-date><volume>4</volume><issue>4</issue><fpage>124</fpage><lpage>128</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бурлакова Е.В., Швец Л.В., Щуко А.Г., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Бурлакова Е.В., Швец Л.В., Щуко А.Г.</copyright-holder><copyright-holder xml:lang="en">Burlakova E.V., Shvets L.V., Shchuko A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/2133">https://www.actabiomedica.ru/jour/article/view/2133</self-uri><abstract><p>Наиболее чувствительным методом оценки изменения зрительных функций у больных оптическим невритом является хроматическая компьютерная периметрия с красной меткой на зелёном фоне.</p><sec><title>Цель исследования</title><p>Цель исследования: оценить эффективность клинических и функциональных методов диагностики оптических невритов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено поперечное, нерандомизированное, всестороннее обследование 53 пациентов в возрасте 19–48 лет (31,65 ± 4,88), соотношение м : ж = 1 : 1,2 с оптическим невритом. Из них 43 случая – пациенты с рассеянным склерозом. Группу контроля составили 37 человек с высокой остротой зрения, соматически здоровые, соответствующие клинической группе по полу и возрасту.</p></sec><sec><title>Результаты</title><p>Результаты. Чувствительность сетчатки у пациентов с оптическим невритом при цветооппонентной периметрии была ниже нормы на 21,96 %. Глубина скотом при оптическом неврите отличалась значительной вариабельностью и находилась в диапазоне от до 2,6 до –19,64 дБ. Уровень дефектов поля зрения зависел от степени выраженности воспалительного процесса и в среднем превышал показатели группы контроля в 4,64 раза. Площадь скотом при оптическом неврите превышала значения группы контроля в 1,81 раза. </p></sec><sec><title>Заключение</title><p>Заключение. Наиболее чувствительным методом оценки изменения зрительных функций у больных оптическим невритом является хроматическая периметрия с красной меткой на зелёном фоне.</p></sec></abstract><trans-abstract xml:lang="en"><p>The most sensitive method for assessing changes in visual functions in patients with optical neuritis is chromatic computer perimetry with a red mark on a green background.</p><sec><title>Aim</title><p>Aim. To evaluate the effectiveness of clinical and functional diagnostic methods for optical neuritis. </p></sec><sec><title>Material and methods</title><p>Material and methods. A cross-sectional, non-randomized, comprehensive examination of 53 patients aged 19–48 years (31.65 ± 4.88), the ratio M : W = 1 : 1.2 with optic neuritis was performed. Of these, 43 cases are patients with multiple sclerosis. The control group consisted of 37 people with high visual acuity, somatically healthy, corresponding to the clinical group by sex and age.</p></sec><sec><title>Results</title><p>Results. Retinal sensitivity in patients with optic neuritis according color contrast perimetry was below the norm by 21.96 %. The depth of blindspots at optical neuritis, differed in significant variability and was in the range from to 2.6 to –19.64 dB. The level of visual field defects depended on the severity of the inflammatory process and, on average, exceeded the indices of the control group by 4.64 times. The area of scotoma in optical neuritis exceeded the values of the control group by 1.81 times.</p></sec><sec><title>Conclusion</title><p>Conclusion. The most sensitive method for assessing changes in visual functions in patients with optical neuritis is chromatic perimetry with a red mark on a green background. Chromatic and achromatic visocontrastometry makes it possible to reveal a significant decrease in indices only in the high frequency range, which characterizes the state of the macular area, which generally indicates the predominant involvement of the retinal ganglion cells in the pathological process.</p><p>The most sensitive method for assessing changes in visual functions in patients with optical neuritis is chromatic perimetry with a red mark on a green background.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>оптический неврит</kwd><kwd>цветооппонентная периметрия</kwd><kwd>визоконтрастометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>optical neuritis</kwd><kwd>color perimetry</kwd><kwd>visocontrastometry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Balcer LJ. Clinical practice. Optic neuritis. 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