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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-1845</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МИКРОБИОЛОГИЯ И ВИРУСОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MICROBIOLOGY AND VIRUSOLOGY</subject></subj-group></article-categories><title-group><article-title>КРАТКАЯ ХАРАКТЕРИСТИКА ШТАММОВ ВИРУСА КЛЕЩЕВОГО ЭНЦЕФАЛИТА ЕВРОПЕЙСКОГО ГЕНОТИПА, ВЫЯВЛЕННЫХ В СИБИРСКОМ РЕГИОНЕ</article-title><trans-title-group xml:lang="en"><trans-title>BRIEF CHARACTERISTIC OF EUROPEAN GENOTYPE TICK-BORNE ENCEPHALITIS VIRUS STRAINS IDENTIFIED IN SIBERIAN REGION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачев</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkachev</surname><given-names>S. E.</given-names></name></name-alternatives><email xlink:type="simple">tkachev@niboch.nsc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">diwerhoz@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джиоев</surname><given-names>Ю. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhioev</surname><given-names>Y. P.</given-names></name></name-alternatives><email xlink:type="simple">alanir07@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Верхозина</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Verkhozina</surname><given-names>M. M.</given-names></name></name-alternatives><email xlink:type="simple">diwerhoz@rambler.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дорощенко</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Doroschenko</surname><given-names>E. K.</given-names></name></name-alternatives><email xlink:type="simple">doroshchenko-virus@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лисак</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lisak</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">lisak.liza@rambler.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сунцова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Suntsova</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">olga_syntsova@list.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Злобин</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zlobin</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">vizlobin@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Парамонов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Paramonov</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">paramonov_a.i@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тикунов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikunov</surname><given-names>A. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ляпунов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyapunov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">liapunov.asp@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тикунова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikunova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ружек</surname><given-names>Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Ruzek</surname><given-names>D. ..</given-names></name></name-alternatives><email xlink:type="simple">ruzekd@paru.cas.cz</email><xref ref-type="aff" rid="aff-6"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт химической биологии и фундаментальной медицины СО РАН</institution></aff><aff xml:lang="en"><institution>Institute of Chemical Biology and Fundamental Medicine SB RAS</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Иркутский государственный медицинский университет (</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical University; Scientific Center for Family Health Problems and Human Reproduction</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Центр гигиены и эпидемиологии в Иркутской области</institution></aff><aff xml:lang="en"><institution>Center for Hygiene and Epidemiology in Irkutsk region</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Научный центр проблем здоровья семьи и репродукции человека</institution></aff><aff xml:lang="en"><institution>Scientific Center for Family Health Problems and Human Reproduction</institution></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Иркутский государственный медицинский университет (</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Институт паразитологии биологического центра Академии наук Республики Чехия; Научно-исследовательский институт ветеринарии</institution></aff><aff xml:lang="en"><institution>Institute of Parasitology of Biological Center of Czech Republic Academy of Sciences; Institute of Veterinary</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>11</month><year>2014</year></pub-date><volume>0</volume><issue>6</issue><fpage>96</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ткачев С.Е., Козлова И.В., Джиоев Ю.П., Верхозина М.М., Дорощенко Е.К., Лисак О.В., Сунцова О.В., Злобин В.И., Парамонов А.И., Тикунов А.Ю., Ляпунов А.В., Тикунова Н.В., Ружек Д..., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Ткачев С.Е., Козлова И.В., Джиоев Ю.П., Верхозина М.М., Дорощенко Е.К., Лисак О.В., Сунцова О.В., Злобин В.И., Парамонов А.И., Тикунов А.Ю., Ляпунов А.В., Тикунова Н.В., Ружек Д.</copyright-holder><copyright-holder xml:lang="en">Tkachev S.E., Kozlova I.V., Dzhioev Y.P., Verkhozina M.M., Doroschenko E.K., Lisak O.V., Suntsova O.V., Zlobin V.I., Paramonov A.I., Tikunov A.Y., Lyapunov A.V., Tikunova N.V., Ruzek D...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/1845">https://www.actabiomedica.ru/jour/article/view/1845</self-uri><abstract><p>При молекулярно-генетическом анализе 13 штаммов ВКЭ европейского генотипа, выделенных на территории Западной и Восточной Сибири, были выявлены две группы, отличающиеся генетически друг от друга и имеющие высокий уровень гомологии последовательностей гена E внутри каждой группы. Тем не менее, для ряда штаммов наблюдалась гетерогенность биологических свойств внутри одной группы.</p></abstract><trans-abstract xml:lang="en"><p>The molecular-genetic analysis of 13 strains of Western genotype TBEV isolated in Western and Eastern Siberia demonstrated two groups of strains differed geneticallyfrom each other and had a high level of E gene sequences homology within each group. Nevertheless, the heterogeneity of biological propertiesfor some strains within a group was observed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вирус клещевого энцефалита</kwd><kwd>западный генотип</kwd><kwd>Западная Сибирь</kwd><kwd>Восточная Сибирь</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tick-borne encephalitis virus</kwd><kwd>gene E genotype Western</kwd><kwd>Western Siberia</kwd><kwd>Eastern Siberia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Демина Т.В., Джиоев Ю.П., Козлова И.В., Верхозина М.М. и др. Генотипы 4 и 5 вируса клещевого энцефалита: особенности структуры геномов возможный сценарий их формирования // Вопросы вирусологии. - 2012. - № 4. - С. 13-19</mixed-citation><mixed-citation xml:lang="en">Демина Т.В., Джиоев Ю.П., Козлова И.В., Верхозина М.М. и др. 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