The article presents a comparative analysis of the effectiveness of various methods of reflexotherapy in patients with arterial hypertension and metabolic disorders. It is shown that the inclusion of therapeutic complexes of different variants of acupuncture significantly change clinical and metabolic parameters (blood pressure level, body mass index, atherogenic index, resistance index to insulin, etc.); the most significant results were obtained using pharmacopuncture with Ubichinon compositum. It was found that the standard method of treatment provides a reliable improvement in lipid metabolism (reduction of atherogenic ratio by 12.6 % and a decrease in the activity of prooxidant processes in the system of lipid peroxidation by 11.8 %, a reliable drop in fasting insulin overproduction by 8.5 %, a decrease in insulin resistance index (an average by 11.0 %). Inclusion of classical acupuncture in treatment complex improves the results of standard therapy: atherogenic index decreased by 22.3 %, index of insulin resistance - by 21.9 %. Wherein marked and significant drop of malondialdehyde and glucose concentrations in the blood (19.8 %) (6.3 %) was marked. The introduction of physiological solution (placebo for pharmacopuncture) into acupuncture points had an impact on the studied biochemical and hormonal parameters approximately to the same extent as the classic acupuncture. At the same time, pharmacopuncture with Ubichinon compositum preparation has led to the most expressed favorable changes in the system of insulin regulation of metabolism of carbohydrates and lipids: atherogenic index and resistance index to insulin decreased respectively by 28.1 % and34.1 % indicating markedsanogenetic character of pharmacopuncture on the body of patients with arterial hypertension and metabolic disorders.