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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-1730</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>КАТАМНЕЗ ДЕТЕЙ С ОТЯГОЩЕННОЙ НАСЛЕДСТВЕННОСТЬЮ ПО ТРОМБОЗАМ</article-title><trans-title-group xml:lang="en"><trans-title>CATAMNESIS OF CHILDREN WITH COMPROMISED HEREDITARY BACKGROUND OF THROMBOSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жданова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhdanova</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">l.zhdanova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Патрушев</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Patrushev</surname><given-names>L. I.</given-names></name></name-alternatives><email xlink:type="simple">patrush@mx.ibch.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгих</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgikh</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">iphr@sbamsr.irk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бимбаев</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Bimbaev</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Бурятский филиал ФГБУ «Научный центр проблем здоровья семьи и репродукции человека» СО РАМН; ФГБОУ ВПО «Бурятский государственный университет»</institution></aff><aff xml:lang="en"><institution>Buryat Branch of Scientific Center of Family Health and Human Reproduction Problems SB RAMS; Buryat State University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУН «Институт биоорганической химии им. М.М. Шемякина и Ю.А. Овчинникова» РАН</institution></aff><aff xml:lang="en"><institution>Institute of Bioorganic Chemistry named after M.M. Shemyakin and Yu.A. Ovchinnikov</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ «Научный центр проблем здоровья семьи и репродукции человека» СО РАМН</institution></aff><aff xml:lang="en"><institution>Scientific Center of Family Health and Human Reproduction Problems</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2014</year></pub-date><volume>0</volume><issue>2</issue><fpage>20</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жданова Л.В., Патрушев Л.И., Долгих В.В., Бимбаев А.Б., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Жданова Л.В., Патрушев Л.И., Долгих В.В., Бимбаев А.Б.</copyright-holder><copyright-holder xml:lang="en">Zhdanova L.V., Patrushev L.I., Dolgikh V.V., Bimbaev A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/1730">https://www.actabiomedica.ru/jour/article/view/1730</self-uri><abstract><p>Исследование посвящено изучению особенностей состояния здоровья детей, у которых родственники I и II линий родства перенесли тромбозы сосудов различного калибра и локализаций до 50 лет жизни. Обследовано 28 детей в возрасте 13,5 ± 4,9 лет. Результаты исследования показали, что 43 % детей внутриутробно перенесли гипоксию в результате хронической фетоплацентарной недостаточности. До 64 % детей имеют отклонения в состоянии здоровья, обуславливающие риск развития тромбозов в будущем: артериальная гипертензия, избыточный вес, клапанная патология сердца. 7 детей к моменту исследования уже перенесли тромбозы сосудов различного калибра и локализаций, сочетание унаследованных генов имело корреляционную связь с развитием тромбозов у потомков (r = 0,24; p = 0,05).</p></abstract><trans-abstract xml:lang="en"><p>The research is dedicated to the study of characteristics of health of children, whose relatives of 1st and 2nd lines suffered thrombosis of vessels of different caliber and localizations before the age of 50. We examined 28 children of 13,5 ± 4,9 years. The results showed that 43 % of children suffered hypoxia in utero caused by chronic fetoplacental insufficiency. Up to 64 % of children have abnormalities in the state of their health, causing the risk of thrombosis in the future: hypertension, obesity, cardiac valve disease. 7 children have already suffered thrombosis in vessels of different caliber and localization by the moment of the study. The combination of inherited genes was correlated with the development of thrombosis in children (r = 0,24, p = 0,05).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>тромбоз</kwd><kwd>наследственные тромбофилии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>thrombosis</kwd><kwd>hereditary thrombophilia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Жданова Л.В., Щербакова М.Ю., Решетняк Т.М. Встречаемость антител к фосфолипидам и генетических тромбофилий у детей без системных заболеваний соединительной ткани // Бюл. 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Oncol. - 2011. - Vol. 33 (4). - P. 261-264.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
