actabiomedicaActa Biomedica ScientificaActa Biomedica Scientifica2541-94202587-9596Scientific Centre for Family Health and Human Reproduction Problemsactabiomedica-1673Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEИзменение функциональной активности нейтрофиль-ных гранулоцитов крови у квалифицированных спортсменовChanges in neutrophilic granulocytes functional activity in trained athletesБазаринК. П.BazarinK. P.kpbazarin@gmail.comСавченкоА. А.SavchenkoA. A.aasavchenko@mail.ruАлександроваЛ. И.AlexandrovaL. I.ifkst@mail.ruФГАОУ ВПО Сибирский федеральный университетSiberian Federal UniversityНИИ Медицинских проблем Севера СО РАМНResearch Institute of Medical Problems of the North of Siberian Branch of Russian Academy of Medical ScienceФГБОУ ВПО Красноярский государственный педагогический университет им. В.П. АстафьеваKrasnoyarsk State Pedagogical University named after V.P. Astafiev201328112013061618Copyright © Базарин К.П., Савченко А.А., Александрова Л.И., 20132013Базарин К.П., Савченко А.А., Александрова Л.И.Bazarin K.P., Savchenko A.A., Alexandrova L.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actabiomedica.ru/jour/article/view/1673

Проведено сравнительное исследование функциональной активности нейтрофилов крови, выраженной через расчетный индекс активации,у спортсменов-ориентировщиков в окончании соревновательного периода и контрольной группы, состоящей из практически здоровых лиц, не испытывающих значительных физических нагрузок. Установлено достоверное снижение индекса активации нейтрофилов в группе спортсменов более чем в 2 раза по отношению к контрольной группе.

This article presents results of comparative research of the functional activity of neutrophilic granulocytes, expressed through a calculated index of activation, in sportsmen going in for orienteering at the end of competitive period and the control group, consisting mostly of healthy people, who do not expose to high physical load. We detected a reliable decrease of the activation index of neutrophils of sportsmen in more than 2 times in comparison to the control group.

спортиммунная системанейтрофилыспонтанная хемилюминесценцияиндуцированная хемилюминесценцияsportimmune systemneutrophilspontaneous chemiluminescenceinduced chemiluminescenceReferencesBoyum A., Ronsen O., Tennfjord V.A., Tollefsen S. et al. Chemiluminescence response of granulocytes from elite athletes during recovery from one or two intense bouts of exercise // Eur. J. Appl. Physiol. - 2002. -Vol. 88 (1-2). - P. 20-28.Boyum A., Ronsen O., Tennfjord V.A., Tollefsen S. et al. Chemiluminescence response of granulocytes from elite athletes during recovery from one or two intense bouts of exercise // Eur. J. Appl. Physiol. - 2002. -Vol. 88 (1-2). - P. 20-28.Chinda D., Nakaji S., Umeda T., Shimoyama T. et al. A competitive marathon race decreases neutrophil functions in athletes // Luminescence. - 2003. -N 18 (6). - P. 324-329.Chinda D., Nakaji S., Umeda T., Shimoyama T. et al. A competitive marathon race decreases neutrophil functions in athletes // Luminescence. - 2003. -N 18 (6). - P. 324-329.Chinda D., Umeda T., Shimoyama T., Kojima A. et al. The acute response of neutrophil function to a bout of judo training // Luminescence. - 2003. - N 18 (5). - P. 278-282.Chinda D., Umeda T., Shimoyama T., Kojima A. et al. The acute response of neutrophil function to a bout of judo training // Luminescence. - 2003. - N 18 (5). - P. 278-282.Gani F., Passalacqua G., Senna G., Mosca F.M. Sport, immune system and respiratory infections. // Eur. Ann. Allergy Clin. Immunol. - 2003. - N 35 (2). - P. 41-46.Gani F., Passalacqua G., Senna G., Mosca F.M. Sport, immune system and respiratory infections. // Eur. Ann. Allergy Clin. Immunol. - 2003. - N 35 (2). - P. 41-46.Horn P.L., Pyne D.B., Hopkins W.G., Barnes C.J. Lower white blood cell counts in elite athletes training for highly aerobic sports // Eur. J. Appl. Physiol. - 2010. -N 110 (5). - P. 925-32.Horn P.L., Pyne D.B., Hopkins W.G., Barnes C.J. Lower white blood cell counts in elite athletes training for highly aerobic sports // Eur. J. Appl. Physiol. - 2010. -N 110 (5). - P. 925-32.Kakanis M.W., Peake J., Brenu E.W., Simmonds M. et al. The open window of susceptibility to infection after acute exercise in healthy young male elite athletes // Exerc. Immunol. Rev. - 2010. - N 16. - P. 119-137.Kakanis M.W., Peake J., Brenu E.W., Simmonds M. et al. The open window of susceptibility to infection after acute exercise in healthy young male elite athletes // Exerc. Immunol. Rev. - 2010. - N 16. - P. 119-137.Levada-Pires A.C., Cury-Boaventura M.F., Gorjäo R., Hirabara S.M. et al. Neutrophil death induced by a triathlon competition in elite athletes // Med. Sci. Sports Exerc. - 2008 - N 40 (8). - P. 1447-1454.Levada-Pires A.C., Cury-Boaventura M.F., Gorjäo R., Hirabara S.M. et al. Neutrophil death induced by a triathlon competition in elite athletes // Med. Sci. Sports Exerc. - 2008 - N 40 (8). - P. 1447-1454.Levada-Pires A.C., Fonseca C.E., Hatanaka E., Alba-Loureiro T. et al. The effect of an adventure race on lymphocyte and neutrophil death // Eur. J. Appl. Physiol. - 2010. - N 109 (3). - P. 447-453.Levada-Pires A.C., Fonseca C.E., Hatanaka E., Alba-Loureiro T. et al. The effect of an adventure race on lymphocyte and neutrophil death // Eur. J. Appl. Physiol. - 2010. - N 109 (3). - P. 447-453.Matsuzaka M., Sugawara N., Nakaji S. Measuring neutrophil functions might be a good predictive marker of overtraining in athletes // Luminescence. - 2008. -N 23 (5). - P. 281-286.Matsuzaka M., Sugawara N., Nakaji S. Measuring neutrophil functions might be a good predictive marker of overtraining in athletes // Luminescence. - 2008. -N 23 (5). - P. 281-286.Mochida N., Umeda T., Yamamoto Y., Tanabe M. et al. The main neutrophil and neutrophil-related functions may compensate for each other following exercise-a finding from training in university judoists // Luminescence. - 2007. - N 22 (1). - P. 20-28.Mochida N., Umeda T., Yamamoto Y., Tanabe M. et al. The main neutrophil and neutrophil-related functions may compensate for each other following exercise-a finding from training in university judoists // Luminescence. - 2007. - N 22 (1). - P. 20-28.Morozov V.I., Pryatkin S.A., Kalinski M.I., Rogozkin V.A. Effect of exercise to exhaustion on myeloperoxidase and lysozyme release from blood neutrophils // Eur. J. Appl. Physiol. - 2003. - N 89 (3-4). -P. 257-262.Morozov V.I., Pryatkin S.A., Kalinski M.I., Rogozkin V.A. Effect of exercise to exhaustion on myeloperoxidase and lysozyme release from blood neutrophils // Eur. J. Appl. Physiol. - 2003. - N 89 (3-4). -P. 257-262.Murakami S., Kurihara S., Koikawa N., Nakamura A. et al. Effects of oral supplementation with cystine and theanine on the immune function of athletes in endurance exercise: randomized, double-blind, placebo-controlled trial // Biosci. Biotechnol. Biochem. - 2009. - N 73 (4). -P. 817-821.Murakami S., Kurihara S., Koikawa N., Nakamura A. et al. Effects of oral supplementation with cystine and theanine on the immune function of athletes in endurance exercise: randomized, double-blind, placebo-controlled trial // Biosci. Biotechnol. Biochem. - 2009. - N 73 (4). -P. 817-821.Peake J.M. Exercise-induced alterations in neutrophil degranulation and respiratory burst activity: possible mechanisms of action // Exerc. Immunol. Rev. - 2002. - N 8. - P. 49-100.Peake J.M. Exercise-induced alterations in neutrophil degranulation and respiratory burst activity: possible mechanisms of action // Exerc. Immunol. Rev. - 2002. - N 8. - P. 49-100.Toumi H., F'guyer S., Best T.M. The role of neutrophils in injury and repair following muscle stretch // J. Anat. - 2006. - N 208 (4). - P. 459-270.Toumi H., F'guyer S., Best T.M. The role of neutrophils in injury and repair following muscle stretch // J. Anat. - 2006. - N 208 (4). - P. 459-270.Yaegaki M., Umeda T., Takahashi I. Measuring neutrophil functions might be a good predictive marker of overtraining in athletes // Luminescence. - 2008. -N 23 (5). - P. 281-286.Yaegaki M., Umeda T., Takahashi I. Measuring neutrophil functions might be a good predictive marker of overtraining in athletes // Luminescence. - 2008. -N 23 (5). - P. 281-286.

The authors declare that there are no conflicts of interest present.