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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-1212</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS OF LITERATURE</subject></subj-group></article-categories><title-group><article-title>МАТРИКСНЫЕ МЕТАЛЛОПРОТЕИНАЗЫ И ТКАНЕВЫЕ ИНГИБИТОРЫ МАТРИКСНЫХ МЕТАЛЛОПРОТЕИНАЗ ПРИ БЕРЕМЕННОСТИ И РОДАХ</article-title><trans-title-group xml:lang="en"><trans-title>MATRIX METALLOPROTEINASES AND TISSUE INHIBITORS OF MATRIX METALLOPROTEINASES DURING PREGNANCY AND DELIVERY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кореновский</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korenovsky</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">timidin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синельникова</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinelnikova</surname><given-names>L. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фильчакова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Filchakova</surname><given-names>O. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабалина</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabalina</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ершова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Yershova</surname><given-names>Ye. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фадеева</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Fadeyeva</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ельчанинова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yelchaninova</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Алтайский государственный медицинский университет» Минздравсоцразвития РФ</institution></aff><aff xml:lang="en"><institution>Altay State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>КГБУЗ «Перинатальный центр (клинический) Алтайского края»</institution></aff><aff xml:lang="en"><institution>Perinatal Center (Clinical) of Altay Region</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2012</year></pub-date><volume>0</volume><issue>5(2)</issue><fpage>146</fpage><lpage>149</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кореновский Ю.В., Синельникова Л.М., Фильчакова О.Н., Шабалина Ю.В., Ершова Е.Г., Фадеева Н.И., Ельчанинова С.А., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Кореновский Ю.В., Синельникова Л.М., Фильчакова О.Н., Шабалина Ю.В., Ершова Е.Г., Фадеева Н.И., Ельчанинова С.А.</copyright-holder><copyright-holder xml:lang="en">Korenovsky Y.V., Sinelnikova L.M., Filchakova O.N., Shabalina Y.V., Yershova Y.G., Fadeyeva N.I., Yelchaninova S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/1212">https://www.actabiomedica.ru/jour/article/view/1212</self-uri><abstract><p>Матриксные металлопротеиназы — главные протеолитические ферменты, разрушающие компоненты внеклеточного матрикса различных тканей. В обзоре рассмотрена роль матриксных металлопротеиназ и тканевых ингибиторов матриксных металлопротеиназ при имплантации, морфогенезе и родах.</p></abstract><trans-abstract xml:lang="en"><p>Matrix metalloproteinases are main proteolytic enzymes breaking down most components of extracellular matrix of various tissues. In the review shows role of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases during implantation, morphogenesis, and. delivery.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>матриксные металлопротеиназы</kwd><kwd>морфогенез</kwd><kwd>беременность</kwd><kwd>роды</kwd></kwd-group><kwd-group xml:lang="en"><kwd>matrix metalloproteinases</kwd><kwd>morphogenesis</kwd><kwd>pregnancy</kwd><kwd>delivery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Alexander C.M., Hansell E.J., Behrendtsen O. et al. 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