actabiomedicaActa Biomedica ScientificaActa Biomedica Scientifica2541-94202587-9596Scientific Centre for Family Health and Human Reproduction Problemsactabiomedica-1210Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWS OF LITERATUREРОЛЬ ИНТЕРФЕРОНОВ В РЕГУЛЯЦИИ ОСТЕОГЕННЫХ И ОСТЕОРЕЗОРБТИВНЫХ ПРОЦЕССОВROLE OF INTERFERONS IN REGULATION OF OSTOGENIC AND OSTEORESORPTIVE PROCESSESДмитриеваЛ. А.DmitrievaL. A.scrrs.irk@gmail.comКоршуноваЕ. Ю.KorshunovaE. Yu.noemail@neicon.ruЛебедевВ. Ф.LebedevV. F.noemail@neicon.ruНаучный центр реконструктивной и восстановительной хирургии СО РАМНScientific Center of Reconstructive and Restorative Surgery SB RAMSГБОУ ВПО «Иркутский государственный медицинский университет» Минздравсоцразвития РФIrkutsk State Medical University20122809201205(2)136140Copyright © Дмитриева Л.А., Коршунова Е.Ю., Лебедев В.Ф., 20122012Дмитриева Л.А., Коршунова Е.Ю., Лебедев В.Ф.Dmitrieva L.A., Korshunova E.Y., Lebedev V.F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actabiomedica.ru/jour/article/view/1210

Bone tissue preserves high metabolic activity during all time of its life. Homeostasis of bone tissue is provided by fine balance between its formation by osteoblasts and its resorption by osteoclasts. There are complex regulatory interrelations between cells of bone differon and. system of interferons, the peculiarities of production of which mediate disturbances of osteoformating and. resorptive components of osteo metabolism at various pathological conditions. The review presents literature data on the role of interferons in regulation of osteogenous and. osteoresorptive processes which opens up the prospective of aimed application of interferons preparations with the purpose of restoration of immunologic imbalance and. bone tissue homeostasis.

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The authors declare that there are no conflicts of interest present.