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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-1117</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ В БИОЛОГИИ И МЕДИЦИНЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL RESEARCHES IN BIOLOGY AND MEDICINE</subject></subj-group></article-categories><title-group><article-title>ИЗУЧЕНИЕ ПАТОГЕНЕТИЧЕСКИХ ОСОБЕННОСТЕЙ ИНФЕКЦИИ, ВЫЗВАННОЙ ВЫСОКОПАТОГЕННЫМ ВИРУСОМ ГИППА A/H5N1 У ДИКИХ УТОК И ДОМАШНИХ КУР</article-title><trans-title-group xml:lang="en"><trans-title>STUDY OF PATHOGENETIC FEATURES INFECTIOUS CAUSED BY HIGHLY PATHOGENIC INFLUENZA VIRUS A/H5N1 IN WILD DUCKS AND DOMESTIC CHICKEN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдуллазянова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdullazyanova</surname><given-names>E. R.</given-names></name></name-alternatives><email xlink:type="simple">elvira.abd@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайковская</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zajkovsmaya</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестопалова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestopalova</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестопалов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestopalov</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственный научный центр вирусологии и биотехнологии «Вектор»</institution></aff><aff xml:lang="en"><institution>Scientific Centre of Virology and Biotechnology «Vector»</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Новосибирский государственный университет</institution></aff><aff xml:lang="en"><institution>Novosiborsk State University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2012</year></pub-date><volume>0</volume><issue>5(1)</issue><fpage>163</fpage><lpage>165</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абдуллазянова Э.Р., Зайковская А.В., Шестопалова Л.В., Шестопалов А.М., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Абдуллазянова Э.Р., Зайковская А.В., Шестопалова Л.В., Шестопалов А.М.</copyright-holder><copyright-holder xml:lang="en">Abdullazyanova E.R., Zajkovsmaya A.V., Shestopalova L.V., Shestopalov A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/1117">https://www.actabiomedica.ru/jour/article/view/1117</self-uri><abstract><p>Изучены изменения в легком, печени и головном мозге у диких уток вида кряква и кур при экспериментальном заражении высокопатогенным, вирусом гриппа А/H5N1. Показано выделение вируса в мазках из глотки, и. клоаки, дан титр вируса в образцах органов. У диких уток изменения в органах носят, дистрофический характер, у домашних кур имеют, дистрофически-некротическую природу.</p></abstract><trans-abstract xml:lang="en"><p>Changes in lung, liver and brain were investigated, in wild, ducks and. domestic chicken under experimental infection caused by highly pathogenic avian Influenza virus A/H5N1. Isolation of virus was demonstrated, in swabs from the throat and. cloaca, virus titers were presented, in patterns of organs. Changes in organs of wild, ducks have dystrophic characteristics, but in domestic chickens are of the dystrophic and necrotic nature.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дикие водоплавающие птицы</kwd><kwd>вирус гриппа A/H5N1</kwd><kwd>патоморфология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>wild aquatic birds</kwd><kwd>Influenza virus A/H5N1</kwd><kwd>pathomorphology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">H5N1 influenza viruses: outbreaks and biological properties / G. Neumann [et al.] // J. Cell Research - 2010. - Vol. 20, Is. 1. - P. 51-61.</mixed-citation><mixed-citation xml:lang="en">H5N1 influenza viruses: outbreaks and biological properties / G. Neumann [et al.] // J. Cell Research - 2010. - Vol. 20, Is. 1. - P. 51-61.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">H5N1 subtype highly pathogenic avian influenza virus isolated from healthy mallard captured in South Korea / H.-R. Kim [et. al.] // J. Vet. Microbiology. - 2011. - Vol. 151. - P. 386 - 389.</mixed-citation><mixed-citation xml:lang="en">H5N1 subtype highly pathogenic avian influenza virus isolated from healthy mallard captured in South Korea / H.-R. Kim [et. al.] // J. Vet. Microbiology. - 2011. - Vol. 151. - P. 386 - 389.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Isolation and characterization of influenza A virus (subtype H5N1) that caused the first highly pathogenic avian influenza outbreak in chicken in Bhutan / S.C. Dubey [et. al.] // J. Vet. Microbiology. -2012. - Vol. 155, Is. 1. - P. 100-105.</mixed-citation><mixed-citation xml:lang="en">Isolation and characterization of influenza A virus (subtype H5N1) that caused the first highly pathogenic avian influenza outbreak in chicken in Bhutan / S.C. Dubey [et. al.] // J. Vet. Microbiology. -2012. - Vol. 155, Is. 1. - P. 100-105.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Межпопуляционные взаимодействия в системе вирусы гриппа А - животные - человек / Д.К. Львов [и др.] // Вопр. вирусологии. - 2005. -Т. 50, № 4. - С. 4-11.</mixed-citation><mixed-citation xml:lang="en">Межпопуляционные взаимодействия в системе вирусы гриппа А - животные - человек / Д.К. Львов [и др.] // Вопр. вирусологии. - 2005. -Т. 50, № 4. - С. 4-11.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Эволюция вирусов гриппа птиц H5N1 с 1997 по 2004 г. в Южной и Юго-Восточной Азии / А.С. Липатов [и др.] // Вопр. вирусологии. - 2005. - Т. 50, № 4. - С. 11 - 17.</mixed-citation><mixed-citation xml:lang="en">Эволюция вирусов гриппа птиц H5N1 с 1997 по 2004 г. в Южной и Юго-Восточной Азии / А.С. Липатов [и др.] // Вопр. вирусологии. - 2005. - Т. 50, № 4. - С. 11 - 17.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
