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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-111</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>КЛИНИЧЕСКАЯ ДИНАМИКА И ДИАГНОСТИКА НЕПСИХОТИЧЕСКИХ АФФЕКТИВНЫХ РАССТРОЙСТВ В СВЕТЕ МНОГОЛЕТНЕГО КАТАМНЕЗА</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL COURSE AND DIAGNOSTICS OF NON-PSYCHOTIC AFFECTIVE DISORDERS BASED ON LONG-TERM CATAMNESIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Собенников</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobennikov</surname><given-names>V. S.</given-names></name></name-alternatives><email xlink:type="simple">vsobennikov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Собенникова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobennikova</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">nikasob@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винокуров</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinokurov</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">evgeniy_vinokurov@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Иркутский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Irkutsk State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2015</year></pub-date><volume>0</volume><issue>5</issue><fpage>35</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Собенников В.С., Собенникова В.В., Винокуров Е.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Собенников В.С., Собенникова В.В., Винокуров Е.В.</copyright-holder><copyright-holder xml:lang="en">Sobennikov V.S., Sobennikova V.V., Vinokurov E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/111">https://www.actabiomedica.ru/jour/article/view/111</self-uri><abstract><p>Целью работы являлось уточнение особенностей диагностики, клиники и течения непсихотических аффективных расстройств на протяжении катамнеза более 5 лет. По материалам архивных историй болезни изучено 47случаев [12 мужчин, 35женщин). Особенностями изученных состояний были полиморфизм симптомов, частота соматизации и коморбидной патологии. При первой госпитализации диагностика лишь в 46,8 % наблюдений соответствовала рубрике F3 (МКБ10), часто определялся двойной диагноз [14 случаев [29,8 %&gt;)). В динамике увеличивалась частота изменения диагноза в пользу биполярного аффективного расстройства 2-го типа [DSM-IV) -с 6,4% до 33,3 % (р &lt; 0,005). Обсуждаются вопросы оптимизации ранней диагностики непсихотических аффективных расстройств.</p></abstract><trans-abstract xml:lang="en"><p>Individual variation in the clinical trajectories of affective disorder may have prognostic and therapeutic implications. We aimed to describe the long-term clinical course and outcome of non-psychotic affective disorder based on 5-year catamnesis. Medical records of 47 patients were studied (12 men, 35 women). The studied cases are characterized by polymorphism of symptoms and high levels of somatization and comorbid disorders. At first hospitalization only 46,8 % of cases diagnosed matched category F3 (ICD-10), a high level of double diagnosis has been described (14 cases - 29,8 %). Subsequent hospitalizations increased frequency of diagnosis of bipolar disorder type 2 (DSM-IV) - from 6,4 % to 33,3 % (p &lt; 0,005). The problem of early recognition of non-psychotic affective disorders was discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>непсихотические аффективные расстройства</kwd><kwd>депрессия</kwd><kwd>биполярное аффективное расстройство</kwd></kwd-group><kwd-group xml:lang="en"><kwd>non-psychotic affective disorders</kwd><kwd>depression</kwd><kwd>bipolar affective disorder</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Краснов В.Н. Расстройства аффективного спектра. - М., Практическая медицина, 2011. - 432 с.</mixed-citation><mixed-citation xml:lang="en">Краснов В.Н. Расстройства аффективного спектра. - М., Практическая медицина, 2011. - 432 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Van Meter AR, Youngstrom EA (2012). Cyclothymic disorder in youth: why is it overlooked, what do we know and where is the field headed? Neuropsychiatry (London), 2 (6), 509-519.</mixed-citation><mixed-citation xml:lang="en">Van Meter AR, Youngstrom EA (2012). Cyclothymic disorder in youth: why is it overlooked, what do we know and where is the field headed? Neuropsychiatry (London), 2 (6), 509-519.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
