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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actabiomedica</journal-id><journal-title-group><journal-title xml:lang="ru">Acta Biomedica Scientifica</journal-title><trans-title-group xml:lang="en"><trans-title>Acta Biomedica Scientifica</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2541-9420</issn><issn pub-type="epub">2587-9596</issn><publisher><publisher-name>Scientific Centre for Family Health and Human Reproduction Problems</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">actabiomedica-1023</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>ЛЕЧЕНИЕ РАННЕЙ ПАРАПРОТЕЗНОЙ ИНФЕКЦИИ ПРИ ЭНДОПРОТЕЗИРОВАНИИ ТАЗОБЕДРЕННОГО СУСТАВА</article-title><trans-title-group xml:lang="en"><trans-title>TREATMENT OF EARLY PERIPROSTHETIC INFECTION AT HIP REPLACEMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольник</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Golnik</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">vgolnik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохоренко</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokhorenko</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">VProhorenko@niito.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">Pavlovdoc@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ «Новосибирский научно-исследовательский институт травматологии и ортопедии» Минздравсоцразвития РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>07</month><year>2012</year></pub-date><volume>0</volume><issue>4(2)</issue><fpage>35</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гольник В.Н., Прохоренко В.М., Павлов В.В., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Гольник В.Н., Прохоренко В.М., Павлов В.В.</copyright-holder><copyright-holder xml:lang="en">Golnik V.N., Prokhorenko V.M., Pavlov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actabiomedica.ru/jour/article/view/1023">https://www.actabiomedica.ru/jour/article/view/1023</self-uri><abstract><p>Проведен анализ результатов лечения больных с ранней парапротезной инфекцией после эндопротезирования тазобедренного сустава с использованием тактики, направленной на сохранение имплантата и функции оперированного сустава, основанной на многоэтапной хирургической санации и клинико-лабораторном мониторинге раневого процесса. Показана эффективность выбранной тактики в 83 % случаев. На основе полученных данных предложен алгоритм лечения ранней парапротезной. инфекции при эндопротезировании тазобедренного сустава, который может быть рекомендован к широкому использованию в клинической практике. </p></abstract><trans-abstract xml:lang="en"><p>We carried out the analysis of results of treatment of patients with early periprosthetic infection after total hip replacement with use of tactics aimed at the preservation of an implant and function of the operated joint, based on a multi-stage surgical rehabilitation, clinical and. laboratory monitoring of the wound healing process. The efficiency of chosen tactics in 83 % of cases was shown. Based on these results an algorithm for treatment of early periprosthetic infection at the hip replacement that can be recommended for widespread use in clinical practice was offered. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>эндопротезирование</kwd><kwd>парапротезная инфекция</kwd><kwd>имплантант-ассоциированная инфекция</kwd><kwd>инфекция области хирургического вмешательства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endoprosthesis replacement</kwd><kwd>periprosthetic infection</kwd><kwd>implant-associated infection</kwd><kwd>surgical site infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ахтямов И.Ф., Кузьмин И.И. Ошибки и осложнения эндопротезирования тазобедренного сустава: руководство для врачей. - Казань, 2006. - 328 с.</mixed-citation><mixed-citation xml:lang="en">Ахтямов И.Ф., Кузьмин И.И. Ошибки и осложнения эндопротезирования тазобедренного сустава: руководство для врачей. - Казань, 2006. - 328 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ключевский В.В. Хирургические методы лечения инфекционных осложнений после эндопротезирования тазобедренного сустава: автореф. дис.. канд. мед. наук. - М., 2007. - 22 с.</mixed-citation><mixed-citation xml:lang="en">Ключевский В.В. Хирургические методы лечения инфекционных осложнений после эндопротезирования тазобедренного сустава: автореф. дис.. канд. мед. наук. - М., 2007. - 22 с.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Прохоренко В.М., Павлов В.В. Инфекционные осложнения при эндопротезировании тазобедренного сустава. - Новосибирск: Наука, 2010. - 179 с.</mixed-citation><mixed-citation xml:lang="en">Прохоренко В.М., Павлов В.В. Инфекционные осложнения при эндопротезировании тазобедренного сустава. - Новосибирск: Наука, 2010. - 179 с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Сидоренко С.В. Роль бактериальных биопленок в патологии человека // Инфекции в хирургии. - 2004. - Т. 2, № 3. - С. 16 - 20.</mixed-citation><mixed-citation xml:lang="en">Сидоренко С.В. Роль бактериальных биопленок в патологии человека // Инфекции в хирургии. - 2004. - Т. 2, № 3. - С. 16 - 20.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Donlan R.M., Costerton J.W. Biofilms: Survival mechanisms of clinically relevant microorganisms // Clinical Microbiology Reviews. - 2002. - Vol. 15, N 2. - P. 167 - 193.</mixed-citation><mixed-citation xml:lang="en">Donlan R.M., Costerton J.W. Biofilms: Survival mechanisms of clinically relevant microorganisms // Clinical Microbiology Reviews. - 2002. - Vol. 15, N 2. - P. 167 - 193.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Estes C.S., Beauchamp C.P., Clarke H.D., Spangehl M.J. A two-stage retention debridement protocol for acute periprosthetic joint infections // Clin. Orthop. Relat. Res. - 2010. - Vol. 468 (8). - P. 2029 - 2038.</mixed-citation><mixed-citation xml:lang="en">Estes C.S., Beauchamp C.P., Clarke H.D., Spangehl M.J. A two-stage retention debridement protocol for acute periprosthetic joint infections // Clin. Orthop. Relat. Res. - 2010. - Vol. 468 (8). - P. 2029 - 2038.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Everts R.J., Chambers S.T., Murdoch D.R. et al. Successful antimicrobial therapy and implant retention for streptococcal infection of prosthetic joints // ANZ J. Surg. - 2004. - Vol. 74, N 4. - P. 210 - 214.</mixed-citation><mixed-citation xml:lang="en">Everts R.J., Chambers S.T., Murdoch D.R. et al. Successful antimicrobial therapy and implant retention for streptococcal infection of prosthetic joints // ANZ J. Surg. - 2004. - Vol. 74, N 4. - P. 210 - 214.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Forsberg J.A., Potter B.K., Cierny G. et al. Diagnosis and management of chronic infection // J. Am. Acad. Orthop. Surg. - 2011. - Vol. 19, Suppl. 1. -P. S8-S19.</mixed-citation><mixed-citation xml:lang="en">Forsberg J.A., Potter B.K., Cierny G. et al. Diagnosis and management of chronic infection // J. Am. Acad. Orthop. Surg. - 2011. - Vol. 19, Suppl. 1. -P. S8-S19.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">James G.A., Swogger E., Wolcott R. et al. Biofilms in chronic wounds // Wound Repair Regen. -2008. - Vol. 16 (1). - P. 37 - 44.</mixed-citation><mixed-citation xml:lang="en">James G.A., Swogger E., Wolcott R. et al. Biofilms in chronic wounds // Wound Repair Regen. -2008. - Vol. 16 (1). - P. 37 - 44.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kienapfel H., Kuhn K.-D. The infected implant. - Springer, 2009, Springer Medizin Verlag Heidelberg, 2009.</mixed-citation><mixed-citation xml:lang="en">Kienapfel H., Kuhn K.-D. The infected implant. - Springer, 2009, Springer Medizin Verlag Heidelberg, 2009.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Parvizi J., Azzam K., Ghanem E., Valle C.D. et al. Periprosthetic infection: A new prognostic classification // 27th Annual Meeting of the EBJIS. -Barcelona, 2008.</mixed-citation><mixed-citation xml:lang="en">Parvizi J., Azzam K., Ghanem E., Valle C.D. et al. Periprosthetic infection: A new prognostic classification // 27th Annual Meeting of the EBJIS. -Barcelona, 2008.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Pignatti G., Nitta S., Rani N. et al. Two stage revision in periprosthetic infection: results of 41 cases // Open Orthop. J. - 2010. - Vol. 4. - P. 193 - 200.</mixed-citation><mixed-citation xml:lang="en">Pignatti G., Nitta S., Rani N. et al. Two stage revision in periprosthetic infection: results of 41 cases // Open Orthop. J. - 2010. - Vol. 4. - P. 193 - 200.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Schmalzried T.P., Amstutz H.C., Au M.K. Dorey F.J. Etiology of deep sepsis in total hip arthroplasty. The significance of hematogenous and recurrent infections // Clin. Orthop. - 1992. - Vol. 280. -P. 200 - 207.</mixed-citation><mixed-citation xml:lang="en">Schmalzried T.P., Amstutz H.C., Au M.K. Dorey F.J. Etiology of deep sepsis in total hip arthroplasty. The significance of hematogenous and recurrent infections // Clin. Orthop. - 1992. - Vol. 280. -P. 200 - 207.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
