The work is devoted to developing of V.N. Druzhinin concept about life variant choice. Variant of a person's life is an integral psychological characteristics of the individual being determined by the type of a person's attitude to life. The basis of "inclusion" in the version of the inner life is the interior activity of choice. Life variant choice is defined as the social conditions of life, and psychological characteristics of the person. Self-attitude is seen as a psychological determinant of choosing the life variant. The aim of the research was to study the characteristics of the self-attitude in the selection of different variants of life. According to the hypothesis, the combination of indicators of the self-attitude and its nature can determine the choice of life variant. The study was carried out using test-questionnaire self-attitude of Panteleyev and authors' diagnostic techniques "Actual version of Life". As a result of empirical and statistical data analysis using Kruskal -Wallis H-criterion it has been proved that the characteristics of the self-attitude differ significantly for various life variants. A combination of self-attitude indicators can determine the life variant. The positive nature of the self-attitude determines the choice of the most effective in terms of adaptation options for life. The negative aspects of the self-attitude are linked with the life variant choice that enable to engage in a social system, but not effective in terms of self-realization in it.